Journal of Immunology Research

HIV-Associated Tuberculosis


Publishing date
15 Dec 2010
Status
Published
Submission deadline
15 Jun 2010

1National Institute for Medical Research, Mill Hill, UK and Institute of Infectious Disease and Molecular Medicine, University of Cape Town, South Africa

2Department of Infectious Diseases, Addenbrooke's Hospital, Cambridge and Department of Medicine, University of Cambridge, UK

3Department of Environmental and Occupational Health, Center for Global Public Health, UMDNJ-School of Public Health, NJ, USA

4Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa


HIV-Associated Tuberculosis

Description

Tuberculosis is an important public health problem and remains a leading cause of death in low- and middle-income countries, with an estimated 9.27 million new cases and 1.7 million deaths worldwide in 2007. HIV infection is the greatest risk factor for developing TB. The devastating association between HIV and TB means that 1.37 million of the new TB cases were amongst HIV-infected people, and one out of four TB deaths was HIV related in 2007. The risk of TB is increased during all stages of HIV infection from about 10% over a lifetime (in HIV-uninfected individuals) to as high as 30% per annum in patients with advanced HIV. These circumstances define the analysis of the immune response to TB in the context of HIV infection as a pressing research priority. With these facts in mind the focus of our special issue will be the immunology of HIV-associated tuberculosis. We invite authors to present original research articles that will reflect and stimulate the continuing efforts to elucidate the protective and pathogenic immune mechanisms in adults and children affected by both HIV and TB. The topics to be covered include, but are not limited to:

  • Epidemiology (with respect to the combined effect of HIV and TB)
  • Interaction between host and pathogens (immune reconstitution inflammatory syndrome; development of TB during antiretroviral therapy)
  • Diagnosis (immunological assays for TB in HIV-infected people; immunological markers to define the risk of TB in HIV-infected people beyond the CD4 count)
  • Treatment advances (TB treatment shortening regimes in the context of HIV infection and problems with drug interactions)
  • Nonvaccination-based prevention strategies (isoniazid preventive therapy in the context of antiretroviral treatment; preventing mother-to-child transmission of HIV infection in the context of TB; microbicides in the context of TB)
  • Vaccination strategies (safety and efficacy of novel TB vaccines in HIV-infected people)
  • Animal models for understanding the combined effect of HIV and TB (e.g., studies on primate models dually infected with TB and SIV)

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/jir/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2011
  • - Article ID 513967
  • - Editorial

Human Immunodeficiency Virus-Associated Tuberculosis

Katalin A. Wilkinson | Stephan Schwander | ... | Graeme Meintjes
  • Special Issue
  • - Volume 2011
  • - Article ID 549023
  • - Research Article

HLA- 57 and Gender Influence the Occurrence of Tuberculosis in HIV Infected People of South India

Latha Jagannathan | Mrinalini Chaturvedi | ... | Vasanthapuram Ravi
  • Special Issue
  • - Volume 2011
  • - Article ID 103917
  • - Review Article

Timing of Antiretroviral Therapy for HIV in the Setting of TB Treatment

Damani A. Piggott | Petros C. Karakousis
  • Special Issue
  • - Volume 2011
  • - Article ID 758350
  • - Research Article

Antiretroviral Treatment-Associated Tuberculosis in a Prospective Cohort of HIV-Infected Patients Starting ART

William Worodria | Marguerite Massinga-Loembe | ... | Robert Colebunders
  • Special Issue
  • - Volume 2011
  • - Article ID 239021
  • - Clinical Study

Clinical Characteristics of Tuberculosis-Associated Immune Reconstitution Inflammatory Syndrome in North Indian Population of HIV/AIDS Patients Receiving HAART

Suman Karmakar | Surendra K. Sharma | ... | Vinay Gulati
  • Special Issue
  • - Volume 2011
  • - Article ID 640309
  • - Clinical Study

T Cell Reactivity against Mycolyl Transferase Antigen 85 of M. tuberculosis in HIV-TB Coinfected Subjects and in AIDS Patients Suffering from Tuberculosis and Nontuberculous Mycobacterial Infections

Pascal Launois | Annie Drowart | ... | Kris Huygen
  • Special Issue
  • - Volume 2011
  • - Article ID 980594
  • - Review Article

Changing Concepts of “Latent Tuberculosis Infection” in Patients Living with HIV Infection

Stephen D. Lawn | Robin Wood | Robert J. Wilkinson
  • Special Issue
  • - Volume 2011
  • - Article ID 585919
  • - Review Article

HIV-Associated Tuberculosis

Kogieleum Naidoo | Kasavan Naidoo | ... | Quarraisha Abdool Karim
  • Special Issue
  • - Volume 2011
  • - Article ID 325295
  • - Clinical Study

Performance of a Whole-Blood Interferon-Gamma Release Assay with Mycobacterium RD1-Specific Antigens among HIV-Infected Persons

Akira Fujita | Atsushi Ajisawa | ... | Toru Mori
  • Special Issue
  • - Volume 2011
  • - Article ID 120278
  • - Research Article

In-Hospital Mortality of Disseminated Tuberculosis in Patients Infected with the Human Immunodeficiency Virus

Rodrigo Pires dos Santos | Caroline Deutschendorf | ... | Luciano Zubaran Goldani
Journal of Immunology Research
 Journal metrics
Acceptance rate40%
Submission to final decision62 days
Acceptance to publication33 days
CiteScore5.100
Impact Factor3.327
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