Journal of Immunology Research

Vaccines and Therapies for Biodefense Agents


Publishing date
18 Jul 2014
Status
Published
Submission deadline
28 Feb 2014

Lead Editor

1Biodefense and Preclinical Evaluation Group, Health Protection Agency (HPA), Porton Down, Salisbury, Wiltshire, UK

2Biomedical Sciences Department, Defence Science and Technology Laboratory (DSTL), Porton Down, Salisbury, Wiltshire, UK

3Virology Department, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), Fort Detrick, Frederick, MD, USA


Vaccines and Therapies for Biodefense Agents

Description

Significant progress has been made in the last 20 years following international effort engaging various government agencies and industry across the world to research and develop vaccines and therapies for biodefense. This has involved new thinking about the process of licensing and relabelling of medical countermeasures without setting up classical human phase III clinical trials. The introduction of the FDA Animal Rule (2002) has propelled the development of preclinical animal models representing the human disease syndrome and the derivation of surrogate markers and correlates of protection.

This special issue focuses on the progress, challenges, and recent advances in the area of biodefense vaccines and therapies by referencing individual pathogens on the CDC select agent list. Potential topics include, but are not limited to:

  • Vaccine strategies
  • Future vaccine developments including “omic” technologies
  • Clinical development and prospects for license through the animal rule/correlates of protection
  • Preclinical animal models
  • Postexposure therapy (including vaccines, antibiotics, immunotherapy, and small molecules)

Before submission authors should carefully read over the journal’s Author Guidelines, which are located at http://www.hindawi.com/journals/jir/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/jir/biod/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2015
  • - Article ID 537319
  • - Editorial

Vaccines and Therapies for Biodefence Agents

Julia A. Tree | E. Diane Williamson | ... | Louise M. Pitt
  • Special Issue
  • - Volume 2015
  • - Article ID 347903
  • - Research Article

Effective Binding of a Phosphatidylserine-Targeting Antibody to Ebola Virus Infected Cells and Purified Virions

S. D. Dowall | V. A. Graham | ... | R. Hewson
  • Special Issue
  • - Volume 2014
  • - Article ID 237043
  • - Review Article

The Impact of “Omic” and Imaging Technologies on Assessing the Host Immune Response to Biodefence Agents

Julia A. Tree | Helen Flick-Smith | ... | Caroline A. Rowland
  • Special Issue
  • - Volume 2014
  • - Article ID 913632
  • - Research Article

Exploring the Innate Immunological Response of an Alternative Nonhuman Primate Model of Infectious Disease; the Common Marmoset

M. Nelson | M. Loveday
  • Special Issue
  • - Volume 2014
  • - Article ID 694717
  • - Research Article

Control of Intracellular Francisella tularensis by Different Cell Types and the Role of Nitric Oxide

Sarah L. Newstead | Amanda J. Gates | ... | Roman A. Lukaszewski
  • Special Issue
  • - Volume 2014
  • - Article ID 807564
  • - Research Article

Efficacy of Primate Humoral Passive Transfer in a Murine Model of Pneumonic Plague Is Mouse Strain-Dependent

V. A. Graham | G. J. Hatch | ... | S. G. P. Funnell
  • Special Issue
  • - Volume 2014
  • - Article ID 341820
  • - Research Article

Multiple Roles of Myd88 in the Immune Response to the Plague F1-V Vaccine and in Protection against an Aerosol Challenge of Yersinia pestis CO92 in Mice

Jennifer L. Dankmeyer | Randy L. Fast | ... | Kei Amemiya
  • Special Issue
  • - Volume 2014
  • - Article ID 395302
  • - Review Article

Approaches to Modelling the Human Immune Response in Transition of Candidates from Research to Development

Diane Williamson
  • Special Issue
  • - Volume 2014
  • - Article ID 308732
  • - Research Article

Fusion-Expressed CTB Improves Both Systemic and Mucosal T-Cell Responses Elicited by an Intranasal DNA Priming/Intramuscular Recombinant Vaccinia Boosting Regimen

Sugan Qiu | Xiaonan Ren | ... | Jianqing Xu
Journal of Immunology Research
 Journal metrics
Acceptance rate40%
Submission to final decision91 days
Acceptance to publication32 days
CiteScore3.330
Impact Factor3.404
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