Journal of Immunology Research

Toll-Like Receptors and Innate Immunity


Publishing date
01 Oct 2019
Status
Closed
Submission deadline
24 May 2019

1Faculty of Sciences of Gafsa, Gafsa, Tunisia

2Habib Bourguiba University Hospital, Sfax, Tunisia

3University of Reading, Reading, UK

This issue is now closed for submissions.
More articles will be published in the near future.

Toll-Like Receptors and Innate Immunity

This issue is now closed for submissions.
More articles will be published in the near future.

Description

Innate immunity is the first line of defense for organisms against invading pathogens. Rapid activation of the innate immune system is important for developing the late stage pathogen specific adaptive immunity mediated by B and T cell activation.

The activation of innate immune cells is largely ensured by a pattern of receptors which recognize specific pathogen-associated molecular patterns (PAMPs). In this context, Toll-like receptors (TLRs) are known to be the most essential players in the activation ofpathogen defense-related signal transduction cascades in immune cells. In addition to their physiological role and the recognition of PAMPs, TLRs are believed to play a role in development and progression of autoimmune disorders, which is at least partly attributed to their ability to recognize endogenous danger-associated molecular patterns (DAMPs).

This special issue invites authors to submit original research articles as well as review articles on the topic of innate immunity and TLRs. The issue particularly welcomes original research articles related to the role of TLRs in inflammatory and autoimmune diseases as well as infection and immunotherapy. Moreover, the issue encourages submission of original research articles and reviews on receptor cooperation or interaction between TLRs and other receptors and manuscripts on endogenous ligands (DAMPs) of TLRs.

Potential topics include but are not limited to the following:

  • TLRs and autoimmune diseases
  • TLRs in inflammation
  • Activation, signaling, and transcriptional modulation of TLRs
  • TLRs in clinical therapy
  • TLR function in innate immune cells
  • Endogenous ligands of Toll-like receptors
  • Receptor cooperation and interaction between TLRs and other receptors

Articles

  • Special Issue
  • - Volume 2020
  • - Article ID 2965697
  • - Research Article

Single Nucleotide Polymorphisms in TLR4 Affect Susceptibility to Tuberculosis in Mexican Population from the State of Veracruz

Enrique Ortega | Sujhey Hernández-Bazán | ... | Javier Fuentes-Dominguez
  • Special Issue
  • - Volume 2020
  • - Article ID 2045860
  • - Review Article

Toll-Like Receptors in Natural Killer Cells and Their Application for Immunotherapy

Ji-Yoon Noh | Suk Ran Yoon | ... | Haiyoung Jung
  • Special Issue
  • - Volume 2019
  • - Article ID 2691808
  • - Research Article

TLR7 Modulated T Cell Response in the Mesenteric Lymph Node of Schistosoma japonicum-Infected C57BL/6 Mice

Jiale Qu | Xiuxue Yu | ... | Jun Huang
  • Special Issue
  • - Volume 2019
  • - Article ID 4078671
  • - Research Article

Analysis of Toll-Like Receptors in Human Milk: Detection of Membrane-Bound and Soluble Forms

Chiara Cattaneo | Alice Caramaschi | ... | Maria Cavaletto
  • Special Issue
  • - Volume 2019
  • - Article ID 2724078
  • - Research Article

The Nod2 Agonist Muramyl Dipeptide Cooperates with the TLR4 Agonist Lipopolysaccharide to Enhance IgG2b Production in Mouse B Cells

Sang-Hoon Lee | Jong-Hwan Park | Seok-Rae Park
  • Special Issue
  • - Volume 2019
  • - Article ID 2826563
  • - Research Article

Functional Polymorphisms and Gene Expression of TLR9 Gene as Protective Factors for Nasopharyngeal Carcinoma Severity and Progression

Macherki Yosra | Souissi Sameh | ... | Hassen Elham
  • Special Issue
  • - Volume 2019
  • - Article ID 1790908
  • - Research Article

43 kDa Glycoprotein (gp43) from Paracoccidioides brasiliensis Induced IL-17A and PGE2 Production by Human Polymorphonuclear Neutrophils: Involvement of TLR2 and TLR4

Taiane Priscila Gardizani | Amanda Manoel Della Coletta | ... | Luciane Alarcão Dias-Melicio
  • Special Issue
  • - Volume 2019
  • - Article ID 1824624
  • - Review Article

The Role of Toll-Like Receptors in Skin Host Defense, Psoriasis, and Atopic Dermatitis

Lixiang Sun | Wenjie Liu | Ling-juan Zhang
  • Special Issue
  • - Volume 2019
  • - Article ID 3562672
  • - Research Article

Innate Immune Responses Associated with Resistance against Haemonchus contortus in Morada Nova Sheep

João Henrique Barbosa Toscano | Cintia Hiromi Okino | ... | Ana Carolina de Souza Chagas
  • Special Issue
  • - Volume 2019
  • - Article ID 3405103
  • - Research Article

Differential Expression of IFN-γ, IL-10, TLR1, and TLR2 and Their Potential Effects on Downgrading Leprosy Reaction and Erythema Nodosum Leprosum

Douglas Eulálio Antunes | Isabela Maria Bernardes Goulart | ... | Luiz Ricardo Goulart
Journal of Immunology Research
 Journal metrics
Acceptance rate40%
Submission to final decision91 days
Acceptance to publication32 days
CiteScore3.330
Impact Factor3.404
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