Journal of Immunology Research

Immunological Features and Clinical Benefits of Conjugate Vaccines against Bacteria


Status
Published

Lead Editor

1University of Genoa, Genoa, Italy

2University of Southampton, Southampton, UK

3University of Barcelona, Barcelona, Spain


Immunological Features and Clinical Benefits of Conjugate Vaccines against Bacteria

Description

Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae are causative agents of invasive and noninvasive diseases with high burden in terms of morbidity and mortality worldwide. The cornerstone for the prevention of these pathologies is vaccination. First generation vaccines were based on bacterial capsular polysaccharides and showed significant gaps in terms of immunologic efficacy and on-field effectiveness. Recently, conjugation technologies have allowed the development of novel vaccines that have demonstrated higher immunogenicity, optimal antibody persistence, and good efficacy in both children and adults. Consequently, the wide use of these formulations determined the control of diseases sustained by the pneumococcus, Haemophilus type b, and groups A, C, Y, and W meningococcus and a radical change of their epidemiological and ecological pictures. We invite investigators to contribute original research articles as well as review articles.

Potential topics include, but are not limited to:

  • Immunological and microbiological features of Streptococcus pneumoniae
  • Immunological and microbiological features of Neisseria meningitidis
  • Immunological and microbiological features of Haemophilus influenzae
  • Immunological features and problems in the use of polysaccharide vaccines
  • History and development of the conjugation technology
  • Immunology of conjugate vaccines (cell-mediated and humoral responses)
  • Conjugate vaccines and immunologic memory
  • Conjugates vaccines and correlates of protection
  • Real world and hypothetical issues in the development of higher valent conjugate vaccines
  • Haemophilus influenzae type b vaccine efficacy and effectiveness
  • Streptococcus pneumoniae conjugate vaccine efficacy and effectiveness
  • Neisseria meningitidis conjugate vaccine efficacy and effectiveness (MenACYW, MenB, MenC)
  • Novel strategies against group BNeisseria meningitidis
  • Immunization strategies across Europe and/or worldwide
  • Immunization strategies for prevention of bacterial infection in immunocompromised children

Articles

  • Special Issue
  • - Volume 2015
  • - Article ID 934504
  • - Editorial

Immunological Features and Clinical Benefits of Conjugate Vaccines against Bacteria

Paolo Durando | Saul N. Faust | Antoni Torres
  • Special Issue
  • - Volume 2015
  • - Article ID 189153
  • - Review Article

How the Knowledge of Interactions between Meningococcus and the Human Immune System Has Been Used to Prepare Effective Neisseria meningitidis Vaccines

R. Gasparini | D. Panatto | ... | D. Amicizia
  • Special Issue
  • - Volume 2015
  • - Article ID 710656
  • - Research Article

Estimation of the Impact of Meningococcal Serogroup C Universal Vaccination in Italy and Suggestions for the Multicomponent Serogroup B Vaccine Introduction

Domenico Martinelli | Francesca Fortunato | ... | Rosa Prato
  • Special Issue
  • - Volume 2015
  • - Article ID 402381
  • - Review Article

Meningococcal B Vaccination (4CMenB) in Infants and Toddlers

Susanna Esposito | Claudia Tagliabue | Samantha Bosis
  • Special Issue
  • - Volume 2015
  • - Article ID 591580
  • - Review Article

Impacts of the 13-Valent Pneumococcal Conjugate Vaccine in Children

Susanna Esposito | Nicola Principi
  • Special Issue
  • - Volume 2015
  • - Article ID 353461
  • - Review Article

Meningococcal Antigen Typing System Development and Application to the Evaluation of Effectiveness of Meningococcal B Vaccine and Possible Use for Other Purposes

Alexander Domnich | Roberto Gasparini | ... | Donatella Panatto
  • Special Issue
  • - Volume 2015
  • - Article ID 394368
  • - Review Article

Nasopharyngeal Bacterial Carriage in the Conjugate Vaccine Era with a Focus on Pneumococci

V. T. Devine | J. M. Jefferies | ... | S. N. Faust
  • Special Issue
  • - Volume 2015
  • - Article ID 206757
  • - Research Article

Impact of Pneumococcal Conjugate Universal Routine Vaccination on Pneumococcal Disease in Italian Children

Francesca Fortunato | Domenico Martinelli | ... | Rosa Prato
Journal of Immunology Research
 Journal metrics
Acceptance rate45%
Submission to final decision61 days
Acceptance to publication37 days
CiteScore5.100
Impact Factor3.327
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