Journal of Immunology Research

Lyme Borreliosis: from Pathogenesis to Diagnosis and Treatment

Publishing date
15 Dec 2011
Submission deadline
15 Jun 2011

Lead Editor

1Lab for Clinical Neurochemistry and Neurochemical Dementia Diagnostics, Department of Psychiatry and Psychotherapy, Universitätsklinikum Erlangen, Erlangen, Germany

2Department of Infectious Diseases, University Medical Centre Ljubljana, Ljubljana, Slovenia

3Institute for Hygiene and Applied Immunology, Medical University of Vienna, Vienna, Austria

Lyme Borreliosis: from Pathogenesis to Diagnosis and Treatment


Lyme borreliosis is a multisystem disease with rather diverse clinical presentation. Most often skin, nervous system, and joints are affected. The disease is caused by spirochetes of the Borrelia burgdorferi sensu lato complex. Lyme borreliosis has been of great interest for researchers as well as clinicians. Although several hundred reports on Lyme borreliosis have been published during the last few years, many issues remain to be clarified including those in the field of innate and adaptive immune response to the control and eradication of B. burgdorferi infection and the management of patients.

For this special issue we invite basic scientists as well as clinicians to submit original research or review articles highlighting recent advances in pathogenesis influencing on diagnosis, management, and prevention of Lyme borreliosis. Potential topics include, but are not limited to:

  • Pathogenesis of Lyme borreliosis
  • Innate and adaptive immune response in Lyme borreliosis
  • Influence of immune response on clinical presentation of Lyme borreliosis
  • Components of immune response potentially useful as biomarkers for Lyme borreliosis
  • Diagnostic and therapeutic approaches in Lyme borreliosis

Before submission authors should carefully read over the journal's Author Guidelines, which are located at Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at according to the following timetable:


  • Special Issue
  • - Volume 2012
  • - Article ID 231657
  • - Editorial

Lyme Borreliosis: From Pathogenesis to Diagnosis and Treatment

Joanna Zajkowska | Piotr Lewczuk | ... | Gerold Stanek
  • Special Issue
  • - Volume 2012
  • - Article ID 504215
  • - Review Article

Hamster and Murine Models of Severe Destructive Lyme Arthritis

Erik Munson | Dean T. Nardelli | ... | Ronald F. Schell
  • Special Issue
  • - Volume 2012
  • - Article ID 349657
  • - Research Article

Contribution of the Infection-Associated Complement Regulator-Acquiring Surface Protein 4 (ErpC) to Complement Resistance of Borrelia burgdorferi

Claudia Hammerschmidt | Teresia Hallström | ... | Peter Kraiczy
  • Special Issue
  • - Volume 2012
  • - Article ID 595427
  • - Research Article

Evaluating Frequency, Diagnostic Quality, and Cost of Lyme Borreliosis Testing in Germany: A Retrospective Model Analysis

I. Müller | M. H. Freitag | ... | K.-P. Hunfeld
  • Special Issue
  • - Volume 2012
  • - Article ID 294587
  • - Research Article

Adaptive and Innate Immune Responsiveness to Borrelia burgdorferi sensu lato in Exposed Asymptomatic Children and Children with Previous Clinical Lyme Borreliosis

Barbro H. Skogman | Sandra Hellberg | ... | Jan Ernerudh
  • Special Issue
  • - Volume 2012
  • - Article ID 138069
  • - Research Article

ELISA-Based Measurement of Antibody Responses and PCR-Based Detection Profiles Can Distinguish between Active Infection and Early Clearance of Borrelia burgdorferi

John J. Lazarus | Akisha L. McCarter | ... | R. Mark Wooten
Journal of Immunology Research
 Journal metrics
See full report
Acceptance rate11%
Submission to final decision121 days
Acceptance to publication27 days
Journal Citation Indicator0.560
Impact Factor4.1
 Submit Check your manuscript for errors before submitting

Article of the Year Award: Impactful research contributions of 2022, as selected by our Chief Editors. Discover the winning articles.