Journal of Immunology Research

Peptide-Based Immunotherapeutics and Vaccines 2019


Publishing date
01 May 2020
Status
Closed
Submission deadline
03 Jan 2020

Lead Editor

1Universidad Complutense de Madrid, Madrid, Spain

2Aston University, Birmingham, UK

3ATR, LLC, Worcester, USA

4National Institute of Infectious Diseases, Tokyo, Japan

This issue is now closed for submissions.
More articles will be published in the near future.

Peptide-Based Immunotherapeutics and Vaccines 2019

This issue is now closed for submissions.
More articles will be published in the near future.

Description

An improved understanding of antigen presentation and recognition has enabled the development of new types of vaccines and immunotherapies based on synthetic peptides encompassing B- and T-cell epitopes. The design of such vaccines takes advantage of emergent computational and experimental technologies that facilitate the identification of epitopes within protein antigens.

Peptide-based vaccines offer several advantages over traditional vaccines. Chiefly, they allow the immune response to focus solely on relevant epitopes, avoiding those that lead to nonprotective responses, immune evasion, or unwanted side effects, such as autoimmunity. However, the development of effective peptide-based vaccines requires overcoming significant difficulties, including identifying optimal delivery routes, overcoming the low immunogenicity of peptides, combining different type of epitopes to engage the humoral and cellular arms of the adaptive immune response, and compensating for the poor population coverage of individual T-cell epitopes due to MHC restriction. Moreover, certain antigenic epitopes, specifically B-cell epitopes, are conformational and need to be mimicked by linear sequences or placed onto suitable spatial frameworks.

We invite authors to submit original research and review articles addressing any of these issues in the development of peptide-based vaccines against infectious diseases, cancer, allergy, and autoimmune diseases.

Potential topics include but are not limited to the following:

  • New advances in epitope prediction and large-scale epitope discovery
  • Current progress in characterizing peptide repertoires presented by tumor and antigen presenting cells
  • New approaches for increasing peptide immunogenicity and optimizing the delivery of peptide-based vaccines
  • Development of peptide-based vaccines for the treatment of infectious diseases
  • Development of prophylactic and therapeutic peptide-based vaccines against cancer
  • Peptide-based immunotherapy for allergic and autoimmune diseases

Articles

  • Special Issue
  • - Volume 2020
  • - Article ID 9794575
  • - Research Article

DNA Vaccine Treatment in Dogs Experimentally Infected with Trypanosoma cruzi

Minerva Arce-Fonseca | Ana C. Carbajal-Hernández | ... | Olivia Rodríguez-Morales
  • Special Issue
  • - Volume 2020
  • - Article ID 2567957
  • - Research Article

Epitope-Based Peptide Vaccine against Glycoprotein G of Nipah Henipavirus Using Immunoinformatics Approaches

Arwa A. Mohammed | Shaza W. Shantier | ... | Mohamed A. Hassan
  • Special Issue
  • - Volume 2020
  • - Article ID 2061609
  • - Research Article

Combined IMIG and Immune Ig Attenuate Allergic Responses in Beagle Dogs

R. M. Gorczynski | T. Maqbool | G. Hoffmann
  • Special Issue
  • - Volume 2020
  • - Article ID 3965061
  • - Research Article

Triggered Immune Response Induced by Antigenic Epitopes Covalently Linked with Immunoadjuvant-Pulsed Dendritic Cells as a Promising Cancer Vaccine

Chumeng Chen | Mohanad Aldarouish | ... | Qijun Qian
  • Special Issue
  • - Volume 2020
  • - Article ID 8202067
  • - Research Article

Development and Validation of a Bordetella pertussis Whole-Genome Screening Strategy

Ricardo da Silva Antunes | Lorenzo G. Quiambao | ... | Alessandro Sette
  • Special Issue
  • - Volume 2020
  • - Article ID 3683782
  • - Research Article

Characterization of a Complex Mixture of Immunomodulator Peptides Obtained from Autologous Urine

Alberto Fragoso | Mérida Pedraza-Jiménez | ... | Emilio Medina-Rivero
  • Special Issue
  • - Volume 2020
  • - Article ID 7235742
  • - Research Article

West Nile Virus Vaccine Design by T Cell Epitope Selection: In Silico Analysis of Conservation, Functional Cross-Reactivity with the Human Genome, and Population Coverage

Frances M. Waller | Pedro A. Reche | Darren R. Flower
  • Special Issue
  • - Volume 2020
  • - Article ID 8060375
  • - Review Article

Peptide-Based Vaccination Therapy for Rheumatic Diseases

Bin Wang | Shiju Chen | ... | Guixiu Shi
  • Special Issue
  • - Volume 2020
  • - Article ID 2074803
  • - Research Article

A Multiple Antigen Peptide Vaccine Containing CD4+ T Cell Epitopes Enhances Humoral Immunity against Trichinella spiralis Infection in Mice

Yuan Gu | Ximeng Sun | ... | Xinping Zhu
  • Special Issue
  • - Volume 2019
  • - Article ID 3832513
  • - Research Article

Preliminary Evaluation of the Safety and Immunogenicity of an Antimalarial Vaccine Candidate Modified Peptide (IMPIPS) Mixture in a Murine Model

Jennifer Lambraño | Hernando Curtidor | ... | Manuel A. Patarroyo
Journal of Immunology Research
 Journal metrics
Acceptance rate40%
Submission to final decision65 days
Acceptance to publication30 days
CiteScore3.330
Impact Factor3.404
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