Journal of Immunology Research

Advances in Computational Immunology


Publishing date
18 Dec 2015
Status
Published
Submission deadline
31 Jul 2015

1University of Catania, Catania, Italy

2Nazarbayev University, Astana, Kazakhstan

3Boston University, Boston, USA


Advances in Computational Immunology

Description

Computational immunology is a field of science that combines mathematical, statistical, data analytics, and modeling approaches to immunology. The glut of data produced by high-throutput instrumentation, notably genomics, transcriptomics, epigenetics, and proteomics methods, require computational tools for acquisition, storage, and analysis of immunological data. To be able to analyze immunological data, we must convert it into computational problems, solve these problems using mathematical and computational approaches, and then translate these results into immunologically meaningful interpretations.

Immunology has embraced data-driven computational and mathematical approaches to help understand the immune system, its disorders, and interaction with infectious agents. Computational immunology covers a broad range of applications. Mathematical models have long been used for modeling immune responses, as well as molecular and cellular interactions, progression of infection, tumor growth, and host-pathogen interactions. The applied arm of computational immunolygy, immunoinformatics, is dedicated to development and application of computational methods and tools for the analyses of immunological data and knowledge extraction using statistical inference and machine learning algorithms. Computational immunology is a key driver that enhances basic and translational immunology by empowering data-driven research.

This special issue intends to collect contributions from immunologists along with mathematicians, bioinformaticians, computational scientists, and engineers to present and discuss latest developments in different subareas of computational immunology, ranging from databases applications to computational vaccine design, modeling, and simulation and their application to basic and clinical immunology.

Potential topics include, but are not limited to:

  • Data analytics
  • Databases
  • Predictive systems
  • Mathematical models of the immune system
  • High-performance computing in immunology
  • Computational vaccine design
  • Design of immunotherapies
  • Diagnostics in cancer immunology
  • Proteogenomics
  • Epigenetics

Articles

  • Special Issue
  • - Volume 2015
  • - Article ID 170920
  • - Editorial

Advances in Computational Immunology

Francesco Pappalardo | Vladimir Brusic | ... | Guanglan Zhang
  • Special Issue
  • - Volume 2015
  • - Article ID 210675
  • - Research Article

Relative Movements of Domains in Large Molecules of the Immune System

Wolfgang Schreiner | Rudolf Karch | ... | Nevena Ilieva
  • Special Issue
  • - Volume 2015
  • - Article ID 738030
  • - Review Article

Current Mathematical Models for Analyzing Anti-Malarial Antibody Data with an Eye to Malaria Elimination and Eradication

Nuno Sepúlveda | Gillian Stresman | ... | Chris J. Drakeley
  • Special Issue
  • - Volume 2015
  • - Article ID 140819
  • - Research Article

MIrExpress: A Database for Gene Coexpression Correlation in Immune Cells Based on Mutual Information and Pearson Correlation

Luman Wang | Qiaochu Mo | Jianxin Wang
  • Special Issue
  • - Volume 2015
  • - Article ID 401956
  • - Research Article

The Role of Aggregates of Therapeutic Protein Products in Immunogenicity: An Evaluation by Mathematical Modeling

Liusong Yin | Xiaoying Chen | ... | Timothy P. Hickling
  • Special Issue
  • - Volume 2015
  • - Article ID 737168
  • - Review Article

Computational Modelling Approaches on Epigenetic Factors in Neurodegenerative and Autoimmune Diseases and Their Mechanistic Analysis

Afroza Khanam Irin | Alpha Tom Kodamullil | ... | Martin Hofmann-Apitius
  • Special Issue
  • - Volume 2015
  • - Article ID 173593
  • - Research Article

Geometry Dynamics of α-Helices in Different Class I Major Histocompatibility Complexes

Reiner Ribarics | Michael Kenn | ... | Wolfgang Schreiner
  • Special Issue
  • - Volume 2015
  • - Article ID 739706
  • - Review Article

Understanding Experimental LCMV Infection of Mice: The Role of Mathematical Models

Gennady Bocharov | Jordi Argilaguet | Andreas Meyerhans
  • Special Issue
  • - Volume 2015
  • - Article ID 323506
  • - Research Article

Utilities for High-Throughput Analysis of B-Cell Clonal Lineages

William D. Lees | Adrian J. Shepherd
  • Special Issue
  • - Volume 2015
  • - Article ID 156241
  • - Review Article

Structural and Computational Biology in the Design of Immunogenic Vaccine Antigens

Lassi Liljeroos | Enrico Malito | ... | Matthew James Bottomley
Journal of Immunology Research
 Journal metrics
Acceptance rate40%
Submission to final decision104 days
Acceptance to publication42 days
CiteScore3.330
Impact Factor3.404
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