Journal of Immunology Research

Immune Responses to RNA viruses

Publishing date
15 Dec 2017
Submission deadline
28 Jul 2017

Lead Editor

1Sultan Qaboos University, Muscat, Oman

2Montreal University, Montreal, Canada

3Albert Einstein College of Medicine, New York, USA

4Paris-Sud University, Paris, France

Immune Responses to RNA viruses


RNA viruses represent a major threat to human health around the globe. Many of these viruses are pandemic and can infect hundreds of millions worldwide causing the death of millions of people every year. RNA viruses, which are known for their pandemic and/or lethal impact, include the human immunodeficiency virus (HIV), the hepatitis C virus (HCV), Ebola virus, Zika virus, influenza viruses, yellow fever virus, dengue virus, rhinoviruses (common cold), human T-lymphotropic virus type 1 (HTLV-I), polio, and measles. There is currently no vaccine for many of these viruses and some of the available vaccines are not highly effective. It is therefore important to understand the mechanisms of the immune responses against these viruses to be able to develop effective vaccines and optimal treatments. Studying the immune responses to RNA viruses with available vaccines as well as the results of vaccine trials will help understand the correlates and parameters that should be considered when designing new vaccines. Hence, it is important to deeply understand the adaptive and the innate immune responses as well as the interaction between them in the context of infections with RNA viruses to reach fruitful conclusions.

The aim of this special issue is to publish contributions in the form of research articles and reviews that address the innate and adaptive immune responses to RNA viruses as well as vaccination strategies against these viruses.

Potential topics include but are not limited to the following:

  • Immune responses to an RNA virus mediate by
    • T and B cells
    • γδ T, NKT, and NK cells
    • Monocyte, macrophage, and dendritic cells
    • Cytokines and chemokines
    • Antibodies and complement
    • Host factors and intracellular molecules in target cells
  • Molecules and mechanisms that shape immune responses to an RNA virus such as
    • Pathogen recognition receptors (PRRs)
    • Immunomodulatory molecules
    • Apoptosis and autophagy
    • Inflammation
    • Immune evasion
    • Coinfection with other pathogens
  • Vaccines and immunotherapeutic strategies designed against an RNA virus
  • Autoimmune diseases related to RNA viruses


  • Special Issue
  • - Volume 2018
  • - Article ID 5473678
  • - Editorial

Immune Responses to RNA Viruses

Elias A. Said | Felipe Diaz-Griffero | ... | Ali A. Al-Jabri
  • Special Issue
  • - Volume 2018
  • - Article ID 9480497
  • - Review Article

Viruses Seen by Our Cells: The Role of Viral RNA Sensors

Elias A. Said | Nicolas Tremblay | ... | Daniel Lamarre
  • Special Issue
  • - Volume 2017
  • - Article ID 8689313
  • - Research Article

Impact of the Polymorphism rs9264942 near the HLA-C Gene on HIV-1 DNA Reservoirs in Asymptomatic Chronically Infected Patients Initiating Antiviral Therapy

Laura Herráiz-Nicuesa | Diana Carolina Hernández-Flórez | ... | Carmen Rodríguez-Sainz
  • Special Issue
  • - Volume 2017
  • - Article ID 1548905
  • - Review Article

SERINC as a Restriction Factor to Inhibit Viral Infectivity and the Interaction with HIV

Gracia Viviana Gonzalez-Enriquez | Martha Escoto-Delgadillo | ... | Blanca Miriam Torres-Mendoza
  • Special Issue
  • - Volume 2017
  • - Article ID 8734504
  • - Review Article

Pulmonary Susceptibility of Neonates to Respiratory Syncytial Virus Infection: A Problem of Innate Immunity?

Carole Drajac | Daphné Laubreton | ... | Delphyne Descamps
  • Special Issue
  • - Volume 2017
  • - Article ID 4128398
  • - Research Article

Immune Dysfunction in HIV: A Possible Role for Pro- and Anti-Inflammatory Cytokines in HIV Staging

Iorhen Ephraim Akase | Bolanle O. P. Musa | ... | Abdullahi Asara Mohammed
Journal of Immunology Research
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