Research Article

Changes in Index of Microcirculatory Resistance during PCI in the Left Anterior Descending Coronary Artery in Relation to Total Length of Implanted Stents

Table 3

Flow indices in relation to total stent length in LAD.

Total stent length in LAD
12–22 mm n = 1423–37 mm n = 1438–78 mm n = 14

Before PCI
 Pa hyperaemia (mm Hg)82 (65–84)76 (61–87)72 (65–88)0.903
 Pd hyperaemia (mm Hg)58 (45–65)50.5 (40–67)49 (41–56)0.242
 FFR0.77 (0.69–0.80)0.74 (0.7–0.77)0.66 (0.46–0.74)0.002
 IMR20 (11–27)16 (9–26)16 (10–20)0.557
 IMRcorr19 (10–25)14 (8–24)14 (10–18)0.329
 CFR2.95 (2.5–3.8)2.8 (1.5–4.1)2.15 (1.2–3.8)0.305
 Tmn baseline (seconds)1.0 (0.65–1.49)0.72 (0.47–1.37)0.89 (0.63–1.13)0.305
 Tmn hyperaemia (seconds)0.32 (0.23–0.54)0.44 (0.2–0.5)0.32 (0.24–0.42)0.750

After PCI
 Pa hyperaemia (mm Hg)72 (64–81)71 (57–84)72 (65–80)0.794
 Pd hyperaemia (mm Hg)64 (55–69)62 (48–73)65 (52–72)0.884
 FFR0.86 (0.84–0.9)0.84 (0.82–0.87)0.86 (0.8–0.9)0.660
 IMR14 (10–17)15 (9–23)22 (14–26)0.118
 IMRcorr13 (10–17)14 (9–22)21 (13–25)0.060
 CFR3.6 (2.5–4.9)3.0 (2–4.7)2.3 (1.5–4.0)0.072
 Tmn baseline (seconds)0.85 (0.58–1.31)0.61 (0.55–0.88)0.72 (0.52–1.22)0.824
 Tmn hyperaemia (seconds)0.20 (0.17–0.3)0.21 (0.17–0.36)0.32 (0.26–0.34)0.045

Median (interquartile range); CFR = coronary flow reserve; FFR = fractional flow reserve; IMR = index of microcirculatory resistance; IMRcorr = corrected IMR; Pa = arterial pressure during hyperaemia; Pd = distal pressure during hyperaemia; Tmn = mean transit time; linear regression; variables log-transformed before analysis.