Table 2: Characteristics of the included studies.

Author (year)Total ParticipantsParticipantsParticipantsFollow-up, weeksPrimary endpoints
(# of FMR)Treatment GroupControl Group

Velazquez, 2015478 (415 FMR)23923948All-cause mortality
Asgar, 201692 (45 FMR)5042144All-cause mortality; Cost-effectiveness metrics
Armeni, 2016383 (383 FMR)23215148Cost-effectiveness metrics
Giannini, 2016120 (NR)606048All-cause mortality
Geis, 2017155 (124 FMR)866948Cardiac remodeling metrics (LVEF, LVESD)
Obaida, 2018304 (304 FMR)152152240Composite: all-cause mortality and HF hospitalizations
Kortlandt, 2018863 (593 FMR)56829596All cause mortality
Stone, 2018614 (614 FMR)30231296HF hospitalizations at 24 months, device related complications at 12 months

FMR: functional mitral regurgitation; LVEF: left ventricular ejection fraction; LVESD: left ventricular end systolic diameter