Hemodynamic and Lesion Characteristics Associated with Discordance between the Instantaneous Wave-Free Ratio and Fractional Flow Reserve
Table 2
Lesion characteristics of the concordant and discordant groups.
iFR ≤0.89 FFR >0.8 Discordance (n = 42)
iFR ≤0.89 FFR ≤0.8 Both positive (n = 139)
iFR >0.89 FFR >0.8 Both negative (n = 85)
iFR >0.89 FFR ≤0.8 Discordance (n = 38)
p-value
Age
68.7 ± 11.6
66.0 ± 10.4
69.2 ± 10.5
66.0 ± 11.0
0.11
Female sex
17 (40.5 %)
16 (11.5%)
21 (24.7 %)
7 (18.4 %)
0.001
Body mass index
23.4 ± 3.8
24.0 ± 5.1
23.1 ± 3.5
24.0 ± 3.4
0.45
Diabetes mellitus, n (%)
28 (66.7 %)
96 (69.1 %)
44 (51.8 %)
18 (47.3 %)
0.02
Hypertension, n (%)
33 (78.6 %)
108 (77.7 %)
65 (76.5 %)
27 (71.1 %)
0.84
Dyslipidemia, n (%)
30 (71.4 %)
93 (66.9 %)
58 (68.2 %)
29 (76.3 %)
0.70
Smoking, n (%)
12 (28.6 %)
61 (43.9 %)
39 (45.8%)
17 (44.7 %)
0.25
Previous myocardial infarction, n (%)
9 (21.4%)
31 (22.3 %)
28 (32.9%)
6 (15.8 %)
0.15
Revascularization, n (%)
19 (45.2 %)
71 (51.1 %)
54 (63.5 %)
21 (55.3 %)
0.18
LVEF, %
49.2 ± 11.6
48.8 ± 10.9
49.7 ± 12.1
51.5 ± 9.6
0.63
GFR, mL/min/1.73 m2
40.3 ± 27.8
37.3 ± 28.0
48.5 ± 27.5
60.0 ± 18.8
<.0001
Hemodialysis, n (%)
11 (26.2%)
55 (39.6 %)
20 (23.5%)
1 (2.6%)
<.0001
iFR, instantaneous wave-free ratio; FFR, fractional flow reserve; LVEF, left ventricular ejection fraction; GFR, glomerular filtration rate. Data are expressed as number (percentage) or mean ± SD.
