Table 4: Univariate and multivariate analysis to evaluate predictors of discordance between iFR and FFR.
(a)

Discordance of iFR ≤0.89 and FFR >0.8
Univariate analysisMultivariate analysis
Odds ratio95% CIp-valueOdds ratio95% CIp-value

Age1.010.98-1.040.34
Female sex3.41.68-6.760.012.841.36-5.960.01
Diabetes mellitus1.320.66-2.620.43
Hypertension1.140.52-2.510.75
Hypercholesterolemia1.140.55-2.340.72
Hemodialysis0.870.42-1.820.71
Smoking0.490.24-1.010.050.640.30-1.370.24
Rate-pressure products1.17‡1.03-1.330.021.17‡1.02-1.340.03
Cardiac index1.101.82-1.470.52
Lesion located in LAD0.810.42-1.550.52
Diameter stenosis0.89†0.74-1.080.23
Reference diameter0.920.49-1.750.80
Lesion length0.62†0.37-1.010.060.57†0.32-1.020.06

(b)

Discordance of iFR >0.89 and FFR ≤0.8
Univariate analysisMultivariate analysis
Odds ratio95% CIp-valueOdds ratio95% CIp-value

Age0.980.95-1.020.44
Female sex0.890.37-2.120.78
Diabetes mellitus0.500.26-1.040.060.570.28-1.160.12
Hypertension0.710.33-1.530.39
Hypercholesterolemia1.510.69-3.340.30
Hemodialysis0.060.01-0.420.0050.070.01-0.530.01
Smoking1.110.56-2.200.44
Rate-pressure products0.83‡0.71-0.980.020.88‡0.74-1.040.13
Cardiac index0.570.35-0.920.010.800.48-1.350.38
Lesion located in LAD1.160.59-2.320.66
Diameter stenosis1.11†0.92-1.350.44
Reference diameter0.870.45-1.710.69
Lesion length1.11†0.70-1.760.64

iFR, instantaneous wave-free ratio; FFR, fractional flow reserve; CI, confidence intervals; LAD, left anterior descending artery.
Per increase 1
†Per increase 10
‡Per increase 1000.