Long-Term Outcomes of Extent of Revascularization in Complex High Risk and Indicated Patients Undergoing Impella-Protected Percutaneous Coronary Intervention: Report from the Roma-Verona Registry
Table 1
Baseline characteristics of study population.
Present Study
PROTECT II
EUROpella
USpella
Number of enrolling centres
2
112
10
18
Number of enrolled patients
86
225
144
175
Age (years), mean±SD
72±10
68±11
72±10
70±10
Gender, males/females
79/7
180/45
117/27
74/101
Cardiovascular Risk Factors, n()
Hypertension
67 (78)
/
97 (67)
/
Dyslipidemia
53 (62)
/
93 (65)
/
Diabetes
38 (44)
117 (52)
62 (43)
82 (47)
Smoking
16 (19)
/
61 (42)
/
Family history of CAD
16 (19)
/
/
/
Renal Failure°
27 (31)
102 (23)
41 (28)
58 (33)
Past Cardiac History, n()
Prior MI
30 (35)
/
76 (53)
98 (56)
Prior PCI
14 (16)
/
/
84 (48)
Prior CABG
19 (22)
85 (38)
42 (29)
49 (28)
Clinical presentation, n()
STEMI
13 (15)
/
/
/
NSTEMI
50 (58)
55 (37)
/
/
SA
23 (27)
93 (63)
/
/
NYHA III-IV, n()
60 (70)
151 (67)
/
115 (66)
LVEF, mean±SD ()
31±9
23±6
/
31±17
LVEF ≤35, n()
67 (78)
216 (100)
92 (64)†
121 (69)
EuroSCORE, mean±SD
9±3
9±6
8±3
/
Lower Tertile (3-7)
30 (35)
Mid Tertile 2 (8-10)
30 (35)
Higher Tertile 3 (11-20)
26 (30)
Unsuitable for surgery ‡, n ()
86 (100)
144 (64)
62 (43)
98 (56)
Angiographic characteristics
Multivessel disease, n (%)
86 (100)
/
118 (82)
155 (89)
Left main disease, n (%)
38 (44)
18 (8)
76 (53) §
89(51)
Syntax Score
31±10
30±13
/
37±16
BCIS-JS
10±2
/
/
/
Randomized Impella arm. † LVEF <40% ‡ On the basis of heart-team discussion. §PCI on left main coronary artery. ° Abnormalities of kidney function (decreased glomerular filtration rate <60 ml/min/1.73m2) or kidney structure (e.g., kidney transplantation). CAD=coronary artery disease; MI=myocardial infarction; PCI=percutaneous coronary intervention; CABG=coronary artery bypass graft; STEMI=ST elevation myocardial infarction; NSTEMI=non-ST elevation myocardial infarction; SA= stable angina; NYHA=New York Heart Association; LVEF=left ventricular ejection fraction; BCIS-JS= The British Cardiovascular Intervention Society myocardial Jeopardy Score.
