Gender-Related Differences in Clinical Characteristics and Outcomes of Premature Coronary Artery Disease: Insight from the FOCUS Registry
Table 1
Baseline characteristics: male versus female.
Variables
Total
Male
Female
p value
(n=1397)
(n=872)
(n=525)
Demographics
Age (y)
51.3 ± 7.0
47.9 ± 5.2
57.0 ± 5.7
<0.001
BMI (kg/m2)
25.1 ± 3.0
25.3 ± 2.9
24.8 ± 3.3
0.009
Cardiac risk factors
Obese
203 (14.5%)
133 (15.3%)
70 (13.3%)
0.324
Current smoking
590 (42.2%)
560 (62.4%)
30 (5.7%)
<0.001
Hypertension
774 (55.5%)
423 (48.5%)
351 (67.0%)
<0.001
Hypercholesterolemia
391 (28.0%)
250 (28.7%)
141 (26.9%)
0.465
Diabetes mellitus
307 (22.0%)
166 (19.0%)
141 (26.9%)
0.001
Clinical history
Previous stroke
34 (2.4%)
17 (1.9%)
17 (3.2%)
0.130
Chronic renal failure
4 (0.3%)
1 (0.1%)
3 (0.6%)
0.303
LVEF≤30%
7 (0.5%)
4 (0.5%)
3 (0.6%)
1.000
Family history of CAD
104 (7.4%)
70 (8.0%)
34 (6.5%)
0.285
Clinical indication of PCI
Stable CAD
198 (14.2%)
115 (13.2%)
83 (15.8%)
0.174
ACS
1199 (85.8%)
757 (86.8%)
442 (84.2%)
0.174
Values are presented as mean ± SD or n (percentage). ACS: acute coronary syndromes; BMI: body mass index; CAD: coronary artery disease; LVEF: left ventricular ejection fractions; and PCI: percutaneous coronary intervention. p≤0.001, p≤0.01, and p≤0.05.
