Comparison of First- and Second-Generation Drug-Eluting Stents in Patients with Acute Myocardial Infarction and Prediabetes Based on the Hemoglobin A1c Level
Table 3
Independent predictors for POCOs and any disease revascularization at 2 years in all patients.
Variables
POCOs
Any disease revascularization
Univariate
Multivariate
Univariate
Multivariate
HR (95% CI)
value
HR (95% CI)
value
HR (95% CI)
value
HR (95% CI)
value
1G-DES vs. 2G-DES
1.616 (1.294–2.017)
<0.001
1.520 (1.213–1.905)
<0.001
2.383 (1.753–3.238)
<0.001
2.228 (1.631–3.043)
<0.001
Age (≥65 years)
1.548 (1.282–1.867)
<0.001
1.318 (1.072–1.620)
0.009
1.024 (0.774–1.355)
0.866
1.109 (0.812–1.515)
0.517
Men
1.269 (1.039–1.550)
0.020
1.030 (0.828–1.282)
0.789
1.097 (0.802–1.501
0.563
1.072 (0.759–1.515)
0.692
LVEF (<50%)
1.652 (1.374–1.986)
<0.001
1.437 (1.191–1.733)
<0.001
1.037 (0.777–1.383)
0.807
1.027 (0.767–1.375)
0.859
Hypertension
1.333 (1.107–1.605)
0.002
1.187 (0.977–1.441)
0.084
1.249 (0.943–1.654)
0.121
1.168 (0.870–1.568)
0.302
Dyslipidemia
1.075 (0.811–1.425)
0.617
1.182 (0.887–1.575)
0.252
1.240 (0.826–1.862)
0.299
1.206 (0.798–1.825)
0.374
CPR on admission
4.004 (3.020–5.309)
<0.001
3.722 (2.799–4.950)
<0.001
1.625 (0.860–3.071)
0.135
1.659 (0.875–3.142)
0.121
Lipid-lowering agent
2.487 (2.038–3.035)
<0.001
2.355 (1.908–2.857)
<0.001
1.503 (1.069–2.114)
0.019
1.514 (1.073–2.137)
0.118
MVD
1.733 (1.430–2.102)
<0.001
1.585 (1.303–1.928)
<0.001
1.852 (1.377–2.491)
<0.001
1.793 (1.328–2.420)
<0.001
ACC/AHA type B2/C lesion
1.141 (0.918–1.419)
0.234
1.131 (0.905–1.413)
0.278
1.014 (0.738–1.392)
0.933
1.062 (0.768–1.469)
0.715
Stent diameter (<3.0 mm)
1.176 (0.967–1.431)
0.104
1.088 (0.891–1.328)
0.407
1.097 (0.812–1.482)
0.548
1.031 (0.760–1.400)
0.843
Stent length (≥28 mm)
1.174 (0.975–1.413)
0.091
1.060 (0.877–1.281)
0.546
1.380 (1.043–1.826)
0.024
1.332 (1.000–1.774)
0.050
POCOs: patient-oriented composite outcomes; HR: hazard ratio; CI, confidence interval; 1G: first-generation; 2G: second-generation; DES: drug-eluting stent; LVEF: left ventricular ejection fraction; CPR: cardiopulmonary resuscitation; MVD: multivessel disease; ACC/AHA: American College of Cardiology/American Heart Association.
