Clinical Study

Evaluation of Left Main Coronary Artery Using Optical Frequency Domain Imaging and Its Pitfalls

Table 2

OFDI analysis of the study population.

All (n = 42)

OFDI characteristics
 LM length (mm)10.1 ± 4.5
 LM reference LA (mm2)14.9 ± 4.8
 Proximal LAD reference LA (mm2)7.8 ± 3.2
 Proximal LCX reference LA (mm2)7.8 ± 4.6
 OFDI signs of LM atherosclerosis32 (76.2%)
 LM stenosis (%) [range]26 ± 18 [7–76]
 Tightest lesion site
  Proximal LM3 (9.4%)
  Mid LM1 (3.1%)
  Distal LM13 (40.6%)
  Ostial LAD11 (34.4%)
  Ostial LCX4 (12.5%)

OFDI imaging analysis
 Global LM analysis
  Quadrants with artifacts/total quadrants1207/13540
  Artifacts (%) [range]8.9 [0–55.6]
  Analyzable quadrants per frame3.6 ± 0.5
 Proximal LM
  Quadrants with artifacts/total quadrants835/4472
  Artifacts (%) [range]18.6 [0–100]
  Analyzable quadrants per frame3.3 ± 1
 Mid LM
  Quadrants with artifacts/total quadrants223/4516
  Artifacts (%) [range]5.8 [0–62.5]
  Analyzable quadrants per frame3.8 ± 0.5
 Distal LM
  Quadrants with artifacts/total quadrants149/4552
  Artifacts (%) [range]3.6 [0–46.6]
  Analyzable quadrants per frame3.9 ± 0.4
 Ostial LAD
  Quadrants with artifacts/total quadrants172/5800
  Artifacts (%) [range]2.6 [0–47.8]
  Analyzable quadrants per frame3.9 ± 0.4
 Ostial LCX
  Quadrants with artifacts/total quadrants0/1124
  Artifacts (%) [range]0 [0–0]
  Analyzable quadrants per frame0 ± 0

CABG = coronary artery bypass graft; eGFR = estimated glomerular filtration rate; LA = lumen area; LAD = left anterior descending artery; LCX = left circumflex artery; LM = left main; OFDI = optical frequency domain imaging.