Research Article

Mechanical and Pharmacological Revascularization Strategies for Prevention of Microvascular Dysfunction in ST-Segment Elevation Myocardial Infarction: Analysis from Index of Microcirculatory Resistance Registry Data

Table 4

Therapeutic strategies for STEMI in study population.

ParameterTotal (N = 160)High IMR (N = 54)Low IMR (N = 106) value

Mechanical strategies
 Stent diameter (mm)3.0 [3.0–3.5]3.0 [2.8–3.5]3.0 [3.0–3.5]0.248
 Stent length (mm)24.0 [18.0–30.0]24.0 [22.0–33.0]23.0 [18.0–28.0]0.090
 Pre balloon dilatation, n (%)118 (73.8%)37 (68.5%)81 (76.4%)0.377
 Post balloon dilatation, n (%)20 (12.5%)9 (16.7%)11 (10.4%)0.376
 Direct stenting, n (%)42 (26.2%)17 (31.5%)25 (23.6%)0.377
 Thrombectomy, n (%)75 (46.9%)28 (51.9%)47 (44.3%)0.464
 Thrombectomy + GP IIb/IIIa inhibitor, n (%)31 (19.4%)12 (22.2%)19 (17.9%)0.611

Pharmacological strategies
 Aspirin, n (%)160 (100.0%)54 (100.0%)106 (100.0%)1.000
 Clopidogrel, n (%)107 (66.9%)43 (79.6%)64 (60.4%)0.023
 Third-generation P2Y12 inhibitors, n (%)53 (33.1%)11 (20.4%)42 (39.6%)0.023
 Morphine, n (%)96 (60.0%)28 (51.9%)68 (64.2%)0.183
 GP IIb/IIIa inhibitor, n (%)34 (21.2%)15 (27.8%)19 (17.9%)0.216

GP, glycoprotein; IMR, index of microcirculatory resistance.