Mechanical and Pharmacological Revascularization Strategies for Prevention of Microvascular Dysfunction in ST-Segment Elevation Myocardial Infarction: Analysis from Index of Microcirculatory Resistance Registry Data

Table 6

Results of univariable and multiple linear regression analysis for therapeutic strategies correlated with IMR value.

Parameter	Univariable analysis			Multiple analysis			Multiple analysis
	β	SE	value	β	SE	value	β	SE	value
Mechanical strategies
Stent diameter	−8.00	4.18	0.057	−9.39	3.94	0.018	−5.36	3.45	0.123
Stent length	0.31	0.15	0.046	0.23	0.14	0.118	−0.03	0.13	0.807
Pre-balloon dilatation	−3.64	3.24	0.264
Post-balloon dilatation	10.44	4.25	0.015	11.40	4.22	0.008	8.30	3.53	0.020
Direct stenting	3.64	3.24	0.264
Thrombectomy	2.60	2.87	0.366
Pharmacological strategies
Third-generation P2Y12 inhibitors	−7.24	2.99	0.017	−10.69	2.91	<0.001	−10.28	2.56	<0.001
Morphine	−4.08	2.92	0.164
GP IIb/IIIa inhibitor	8.49	3.48	0.016	8.51	3.38	0.013	−0.98	3.50	0.756

β, unstandardized coefficients; GP, glycoprotein; SE, standard error. Multiple regression analysis adjusted for age, sex, Killip class, symptom onset to hospital time, peak troponin-I level, multivessel disease, final thrombolysis in myocardial infarction myocardial perfusion grade, and presence of distal embolization.