Rate Pressure Products Affect the Relationship between the Fractional Flow Reserve and Instantaneous Wave-Free Ratio
Table 2
Lesion characteristics divided by the median of the rate pressure products.
Low-RPP group (n = 129)
High-RPP group (n = 130)
value
Age
67.8 ± 11.4
70.8 ± 9.0
0.02
Female
23 (17.8%)
40 (30.8%)
0.02
Body mass index (kg/m2)
23.7 ± 3.8
23.9 ± 3.6
0.74
Diabetes mellitus
68 (52.7%)
83 (63.9%)
0.08
Hypertension
92 (71.3%)
98 (75.4%)
0.48
Hyperlipidemia
95 (73.6%)
83 (63.9%)
0.11
Smoking
59 (45.7%)
37 (28.5%)
0.005
Prior myocardial infarction
33 (25.6%)
49 (37.7%)
0.045
Revascularization
78 (60.5%)
68 (52.3%)
0.21
LVEF (%)
49.9 ± 10.6
51.9 ± 8.7
0.10
LVMI (g/m2)
98.7 ± 29.8
91.5 ± 30.6
0.11
E/e′
12.5 ± 4.5
14.1 ± 6.4
0.048
Chronic kidney disease (>stage II)
69 (53.5%)
71 (54.6%)
0.9
GFR (mL/min/1.73 m2)
60.9 ± 17.1
58.0 ± 17.2
0.18
Percent diameter stenosis
63.6 ± 17.4
63.0 ± 18.3
0.77
Left anterior descending artery
78 (60.5%)
69 (53.1%)
0.26
Circumflex artery
24 (18.6%)
30 (23.1%)
0.44
Right coronary artery
27 (20.9%)
31 (23.9%)
0.66
FFR
0.77 ± 0.11
0.78 ± 0.12
0.51
iFR
0.87 ± 0.13
0.84 ± 0.16
0.09
Percent diameter stenosis
64 ± 17
63 ± 18
0.77
Lesion diameter (mm)
17.7 ± 6.9
18.5 ± 6.9
0.32
Reference diameter (mm)
2.7 ± 0.5
2.6 ± 0.5
0.06
Diffuse/tandem lesion
37 (28.7%)
37 (28.7%)
0.89
Rate pressure products
6981 ± 123
10392 ± 122
<0.0001
Systolic blood pressure (mmHg)
111 ± 19.0
138 ± 19.9
<0.0001
Heart rate (beats/minute)
63.3 ± 8.4
76.0 ± 12.2
<0.0001
RPP, rate pressure products; LVEF, left ventricular ejection fraction; LVMI, left ventricular mass index; GFR, glomerular filtration rate; FFR, fractional flow reserve; iFR, instantaneous wave-free ratio. Data are expressed as mean ± standard deviation or as number (percentage).
