Journal of Interventional Cardiology / 2020 / Article / Tab 1

Research Article

Analysis of Atrial Fibrillation Treatment Regimes in a Multicenter Cohort of Transcatheter Edge-to-Edge Mitral Valve Repair Patients

Table 1

Clinical characteristics and heart failure medication.

Total, n = 506Non-AF, n = 133Permanent AF, n = 152Nonpermanent AF, n = 221 value

Age (years)78.1 ± 7.877.4 ± 9.179.1 ± 6.977.9 ± 7.60.2926
Male sex62.9%60.9%71.1%58.4%0.012
EuroSCORE II (IQR)20.0% (23.0)19.1% (21.9)20.1% (22.8)19.6% (23.3)0.74
STS risk score (IQR)7.4% (8.8)7.3% (8.9)8.5% (10.1)6.7% (8.5)0.5924
NYHA class I
NYHA class II
NYHA class III
NYHA class IV
0.2%
4.7%
71.0%
24.1%
0.0%
5.3%
73.7%
21.0%
0.0%
3.9%
70.4%
25.7%
0.5%
5.0%
69.6%
24.9%
0.71
Chronic obstructive pulmonary disease20.6%22.6%23.0%17.7%0.5
Coronary artery disease67.0%77.4%64.5%62.4%0.0028
Prior cardiac bypass surgery26.7%35.3%25.0%22.6%0.0085
Prior percutaneous coronary intervention55.1%62.4%48.7%55.2%0.049
Diabetes mellitus33.4%35.3%36.2%30.3%0.69
Art. hypertension80.0%79.7%81.6%79.2%0.91
Prior stroke10.9%11.3%11.2%10.4%0.86
Preexisting ICD26.9%26.3%25.7%28.1%0.94
Preexisting CRT11.7%11.3%9.2%13.6%0.43
Glomerular filtration rate (mL/min)47.4 ± 20.250.0 ± 22.047.9 ± 20.045.5 ± 19.20.1
NT-pro BNP (ng/L)2 945.0 ± 4 902.02 960.0 ± 5 871.02 921.0 ± 4 687.02 951.0 ± 4 304.00.41
LV function > 45%
LV function 30–44%
LV function < 30%
38.7%
34.6%
26.7%
30.1%
38.3%
31.6%
44.1%
33.6%
22.3%
40.3%
33.0%
26.7%
0.053
TR grade III18.8%11.3%29.6%15.8%0.0006
Degenerative MR etiology
Functional MR etiology
Combined MR etiology
27.5%
64.6%
7.9%
27.1%
65.4%
7.5%
26.3%
65.8%
7.9%
28.5%
63.4%
8.1%
0.96

Heart failure medication
ACE/AT1 inhibitors74.1%72.9%72.4%76.2%0.6
ARN inhibitor7.9%7.5%8.6%7.7%0.93
Beta blockers87.9%87.2%87.5%88.7%0.72
Loop diuretics89.5%87.2%90.8%90.1%0.33
Thiazide diuretics21.3%21.8%25.7%18.1%0.21
Aldosterone antagonists48.0%47.4%47.4%48.9%0.91
Ivabradine1.4%3.8%0.0%0.9%0.023
Digitalis7.7%0.0%17.8%5.4%<0.0001

Data presented as mean ± SD or median with interquartile range (IQR). AF, atrial fibrillation; ICD, implantable cardioverter defibrillator; CRT, cardiac resynchronization therapy; TR, tricuspid regurgitation; MR, mitral regurgitation; ACE, angiotensin-converting enzyme; AT1, angiotensin II type 1 receptor; ARN, angiotensin receptor neprilysin. p values describe differences between patients without AF and with permanent and nonpermanent AF. The bold values indicate the significance of p values.

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