Research Article

Efficacy of Low-Pressure Inflation of Oversized Drug-Coated Balloon for Coronary Artery Disease

Table 3

Baseline characteristics of patients, lesions, and procedure in the propensity-matched cohorts.

VariablesLP group lesions (n = 125)SP group lesions (n = 125) value

Number of patients108113
Age (years)69.1 ± 9.570.1 ± 9.90.48
Male (%)72 (66.7)89 (78.8)0.05
Smoking (%)29 (26.9)22 (19.5)0.21
Diabetes (%)60 (55.6)60 (53.1)0.79
Hypertension (%)78 (72.2)83 (73.5)0.89
Hyperlipidemia (%)72 (66.7)80 (70.8)0.56
Chronic kidney disease (%)25 (23.1)23 (20.4)0.63
Hemodialysis patients (%)12 (11.1)10 (8.8)0.66
AMI (%)5 (4.6)7 (6.2)0.77
Previous MI (%)25 (23.1)31 (27.4)0.54
Previous CABG (%)8 (7.4)10 (8.8)0.81
PAD (%)14 (13.0)8 (7.1)0.18
Target vessel, n (%)0.92
 LMT3 (2.4)3 (2.4)
 LAD49 (39.2)53 (42.4)
 RCA37 (29.6)38 (30.4)
 LCX36 (28.8)31 (24.8)
Lesion anatomy
 Type B2/C (%)96 (76.8)92 (73.6)0.90
 Ostial (%)36 (28.8)39 (31.2)0.78
 Bifurcation (%)68 (54.4)68 (54.4)1.00
 CTO (%)11 (8.8)9 (7.2)0.82
Calcification (%) (visual assessment)0.96
 None53 (42.4)50 (40.0)
 Mild22 (17.6)24 (19.2)
 Moderate18 (14.4)20 (16.0)
 Severe32 (25.6)31 (24.8)
Procedural devices
 DCA (%)8 (6.4)4 (3.2)0.38
 PTCRA (%)38 (30.4)38 (30.4)1.00
 B/A ratio0.75 ± 0.180.71 ± 0.170.31
Drug-coated balloon
 DCB/A ratio1.11 (0.19)1.03 (0.17)0.001
 Inflation pressure (atm)2.5 (1.2)7.0 (2.1)<0.001
 Inflation time (sec)72.3 (42.4)64.4 (34.9)0.11

AMI, acute myocardial infarction; B/A ratio, burr/artery ratio; CABG, coronary artery bypass graft surgery; CTO, chronic total occlusion; DCB, drug-coated balloon; DCB/A ratio, DCB/artery ratio; LAD, left anterior descending artery; LMT, left main trunk; LCX, left circumflex artery; MI, myocardial infarction; MLD, minimal lumen diameter; PAD, peripheral artery diseases; RCA, right coronary artery.