Comparison of Two Percutaneous Atrial Septal Defect Occluders for Device Healing and Nickel Release in a Chronic Porcine Model

Figure 2

Macroscopic aspects of the 2 occluder devices with different implantation times. Photos of the devices were taken immediately after sacrifice and dissection of the hearts. (a) Superficial device coverage in an ASO 1 month after implantation (right atrial side). (b) Advanced device coverage on the right atrial disk of a Hyperion occluder 3 months after implantation. (c) Aspect of the left atrial disk of an ASO 1 month after implant, the covering tissue is predominantly observed on device periphery bordering the defect edges. (d) Advanced device coverage of a Hyperion occluder 3 months after implant, left atrial disk.

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