Research Article

Comparison of Two Percutaneous Atrial Septal Defect Occluders for Device Healing and Nickel Release in a Chronic Porcine Model

Table 3

Median (range) serum levels of nickel along the study period.

J0 (ng/mL)J3 (ng/mL)Before sacrifice (ng/mL)

ASO 1 month (n = 3)4 (0–4.5)4 (3.5–4.7)5 (5.1–6.3)0.066
ASO 3 months (n = 3)4 (3.5–5.6)5 (3.5–6)5 (4.6–6.7)0.213
Hyperion 1 month (n = 3)5 (4.8–6.5)5 (5–5.6)5 (4.4–5.5)0.837
Hyperion 3 months (n = 3)3 (0–6.4)4 (0–5.4)5 (4.9–5.7)0.415