Combined Therapy of Catheter Ablation and Left Atrial Appendage Closure for Patients with Atrial Fibrillation: A Case-Control Study
Table 1
Baseline characteristics of the study population before propensity score matching.
Combined (n = 76)
CA-only (n = 549)
LAAC-only (n = 142)
†
Female
37 (48.7)
285 (51.9)
0.598
67 (47.2)
0.833
Age (years)
69.9 ± 7.9
65.2 ± 7.8
<0.001
72.7 ± 8.4
0.019
BMI (kg/m2)
24.6 ± 3.2
24.9 ± 3.9
0.551
24.1 ± 3.0
0.274
Paroxysmal AF
37 (48.7)
344 (62.7)
0.019
30 (21.1)
<0.001
Persistent AF
39 (51.3)
205 (37.3)
0.019
112 (78.9)
<0.001
Coronary artery disease
16 (21.1)
74 (13.5)
0.246
37 (26.1)
0.204
Hypertension
56 (73.7)
358 (65.2)
0.143
118 (83.1)
0.099
Heart failure
23 (30.3)
68 (12.4)
<0.001
36 (25.4)
0.437
Diabetes mellitus
14 (18.4)
87 (15.8)
0.568
37 (26.1)
0.204
Previous stroke/TIA/TE
23 (30.3)
63 (11.5)
<0.001
35 (24.6)
0.371
Left atrial diameter (mm)
42.7 ± 5.7
38.4 ± 5.5
<0.001
44.7 ± 6.0
0.023
LVEF (%)
63.9 ± 6.3
64.8 ± 6.8
0.271
62.2 ± 7.4
0.104
CHA2DS2-VASc score
3.6 ± 1.3
2.5 ± 1.5
<0.001
3.9 ± 1.3
0.122
HAS-BLED score
3.3 ± 1.1
1.7 ± 0.9
<0.001
3.5 ± 1.1
0.105
Comparison between the combined group and the CA-only group. †Comparison between the combined group and the LAAC-only group. Values are mean ± SD or n (%) as appropriate. AF, atrial fibrillation; BMI, body mass index; CA, catheter ablation; LAA, left atrial appendage; LAAC, left atrial appendage closure; LVEF, left ventricular ejection fraction; TIA, transient ischemic attacks; TE, thromboembolism.
