Clinical Study

Combined Therapy of Catheter Ablation and Left Atrial Appendage Closure for Patients with Atrial Fibrillation: A Case-Control Study

Table 2

Baseline characteristics of the study population after propensity score matching.

Combined (n = 76)CA-only (n = 76)LAAC-only (n = 76)

Female37 (48.7)40 (52.6)0.62638 (50.0)0.871
Age (years)69.9 ± 7.969.5 ± 7.80.70371.36 ± 8.90.300
BMI (kg/m2)24.6 ± 3.224.9 ± 3.70.54324.3 ± 3.30.644
Paroxysmal AF37 (48.7)38 (50.0)0.87127 (35.5)0.100
Persistent AF39 (51.3)38 (50.0)0.87149 (64.5)0.100
Coronary artery disease16 (21.1)15 (19.7)0.84018 (23.7)0.426
Hypertension56 (73.7)54 (71.1)0.71757 (75.0)0.853
Heart failure23 (30.3)21 (27.6)0.72119 (25.0)0.468
Diabetes mellitus14 (18.4)15 (19.7)0.83615 (19.7)0.836
Previous stroke/TIA/TE23 (30.3)15 (19.7)0.13420 (26.3)0.589
Left atrial diameter (mm)42.7 ± 5.741.7 ± 4.90.22644.1 ± 5.90.163
LVEF (%)63.9 ± 6.364.2 ± 5.40.74662.7 ± 6.90.273
CHA2DS2-VASc score3.6 ± 1.33.4 ± 1.40.4843.7 ± 1.40.719
HAS-BLED score3.3 ± 1.12.6 ± 0.9<0.0013.4 ± 1.10.413

Comparison between the combined group and the CA-only group. Comparison between the combined group and the LAAC-only group. Values are mean ± SD or n (%) as appropriate. AF, atrial fibrillation; BMI, body mass index; CA, catheter ablation; LAA, left atrial appendage; LAAC, left atrial appendage closure; LVEF, left ventricular ejection fraction; TIA, transient ischemic attacks; TE, thromboembolism.