Clinical Study

Combined Therapy of Catheter Ablation and Left Atrial Appendage Closure for Patients with Atrial Fibrillation: A Case-Control Study

Table 4

Left atrial appendage closure and device follow-up.

Combined (n = 76)LAAC-only (n = 76)

Morphology of LAA
 Cauliflower48 (63.2)52 (68.4)0.494
 Chicken wing16 (21.1)8 (10.5)0.075
 Cactus6 (7.9)9 (11.8)0.415
 Windsock6 (7.9)7 (9.2)0.772
Procedure time (min)26.1 ± 6.428.0 ± 8.70.149
Fluoroscopy time (min)4.9 ± 1.94.5 ± 2.40.273
LAA ostium width (mm)22.9 ± 3.123.5 ± 3.40.220
Device size (mm)29.0 ± 3.029.1 ± 3.20.876
Number of device size changes per patient
 073 (96.1)71 (93.4)0.468
 13 (3.9)5 (6.6)0.468
 20 (0.0)0 (0.0)
Device compression (%)19.6 ± 4.518.4 ± 4.30.085
Successful implantation76 (100)76 (100)
Peridevice leak at implantation
 Complete occlusion of LAA72 (94.7)70 (92.1)0.513
 Leak ≤5 mm4 (5.3)6 (7.9)0.513
 Leak >5 mm0 (0.0)0 (0.0)
Complications3 (3.9)2 (2.6)0.650
 Pericardial effusion1 (1.3)0 (0.0)0.317
 Stroke0 (0.0)0 (0.0)
 Coronary air embolism0 (0.0)1 (1.3)0.317
 Bleeding0 (0.0)0 (0.0)
 Death0 (0.0)0 (0.0)
 Complications of vascular access2 (2.6)1 (1.3)0.561
Peridevice leak at 45 days
 Complete occlusion of LAA63 (82.9)65 (85.5)0.656
 New peridevice leaks10 (13.2)7 (9.2)0.440
 Persistent peridevice leaks3 (3.9)4 (5.3)0.699
 Device-associated thrombosis0 (0.0)1 (1.3)0.317
Average follow-up (months)24.0 ± 5.224.1 ± 4.90.961
Follow-up events3 (3.9)2 (2.6)0.650
 Ischemic stroke events1 (1.3)0 (0.0)0.317
 Bleeding events2 (2.6)2 (2.6)1.000

The procedure and fluoroscopy time were calculated from the WATCHMAN access sheath exchange to the end of the procedure. Values are mean ± SD or n (%) as appropriate. AF, atrial fibrillation; LAA, left atrial appendage; LAAC, left atrial appendage closure.