Pre-Emptive OCT-Guided Angioplasty of Vulnerable Intermediate Coronary Lesions: Results from the Prematurely Halted PECTUS-Trial

Table 4

Clinical events.

No.	Group	Target segment	FFR of target lesion	Time after randomisation	Event	MACE	Target lesion related
1 (1)	BVS	LAD-mid (7)	0.82	During BVS implant	Cardiac arrest due to pulseless electrical activity during BVS implantation, for which chest compressions were performed for 1 minute and atropine was given, after which return of spontaneous circulation occurred. No mechanical complication was seen. Postprocedural troponin values were not elevated. Episode was attributed to a vagal reaction.	No	Yes
1 (2)	BVS	LAD-mid (7)	0.82	6 months	Elective PCI of proximal and distal RCA (in-stent restenosis distal RCA) because of progressive angina. No pre-intervention FFR was performed because stenosis in distal RCA was 90%.	No	No
2	BVS	LAD-mid (7)	0.81	4 months	Cardiac arrest due to ventricular fibrillation. ICA shows left main coronary artery occlusion, for which PCI was performed. OCT shows good patency of BVS in the mid LAD.	Yes	No
3	BVS	LAD-mid (7)	0.84	24 months	Non-cardiac death due to obstruction hydrocephalus caused by metastasized lung carcinoma.	Yes	No
4	BVS	RCA-prox (1)	0.93	23 months	Elective PCI of LAD-mid because of stable angina.	No	No
5	BVS	LAD-mid (7)	0.86	8 days	Infected hematoma of the femoral puncture site/closure device.	No	No
6	BVS	Cx-mid (13)	0.95	15 months	STEMI with PCI of distal RCA (culprit). Additional occlusion of a small MO2 branch. This occlusion was not intervened upon as patient was free of complaints after PCI of the RCA. BVS in the mid-Cx was patent.	Yes	No
7	OMT	LAD-mid (7)	0.87	12 months	Non-cardiac death due to aspiration pneumonia in patient with lymphoma and metastasized squamous cell carcinoma.	Yes	No
8	OMT	Cx-mid (13)	1.00	24 months	Hospital admission with chest pain and slightly elevated cardiac troponin levels without rise/fall. ICA showed no obstructive coronary artery disease. Complaints were attributed to hypertension.	No	No
9	OMT	Cx-prox (1)	0.83	22 months	Lobectomy for newly diagnosed lung carcinoma.	No	No
10	OMT	MO1 (12)	0.97	Same day as randomisation	Transient binocular diplopia after ICA.	No	No
11	OMT	LAD-mid (7)	0.89	24 months	Elective PCI of the mid LAD (target segment) and proximal RCA due to stable angina and optimisation for esophageal cancer-related chemotherapy. No pre-intervention FFR was performed because the wire could not pass the mid-LAD.	No	Yes

BVS, bioresorbable vascular scaffold, Cx, circumflex artery, FFR, fractional flow reserve, ICA, invasive coronary angiography, LAD, left anterior descending artery, MACE, major adverse cardiac event, MLA, minimal lumen area, MO, obtuse marginal artery, OCT, optical coherence tomography, OMT, optimal medicinal therapy, PCI, percutaneous coronary intervention, RCA, right coronary artery, STEMI, ST-elevation myocardial infarction.