Vessel Fractional Flow Reserve and Graft Vasculopathy in Heart Transplant Recipients

Table 3

Functional characteristics according to the CAV grade.

	CAV 0; (n = 23)	CAV 1; (n = 12)	CAV 2; (n = 4)	CAV 3; (n = 8)	value
vFFR, median (IQR)	0.84 (0.80, 0.88)	0.76 (0.70, 0.89)	0.72 (0.53, 0.80)	0.54 (0.47, 0.78)	0.009
Lesion length (mm), median (IQR)	26.0 (14.7, 45.5)	22.2 (17.8, 30.0)	31.2 (29.0, 70.7)	36.2 (18.8, 48.4)	0.51
MLD (mm), median (IQR)	1.53 (1.26, 1.72)	1.65 (0.89, 1.73)	0.92 (0.88, 1.62)	0.80 (0.59, 1.38)	0.08
Diameter stenosis (%), median (IQR)	31.0 (25.0, 42.0)	36.0 (31.0, 43.0)	57.0 (56.5, 60.5)	64.0 (59.5, 72.5)	<0.001
Reference diameter (mm), median (IQR)	2.29 (2.03, 2.70)	2.51 (1.54, 2.79)	2.33 (2.23, 3.79)	2.88 (1.67, 3.51)	0.85

CAV, cardiac allograft vasculopathy; vFFR, vessel fractional flow reserve derived from angiography; IQR, interquartile range; and MLD, minimal lumen diameter.