Research Article
New Discovery of Left Atrial Macroreentry Tachycardia: Originating from the Spontaneous Scarring of Left Atrial Anterior Wall
| | Patients characteristics | Study group (N = 9) | Control group (N = 83) | value |
| | Age (yrs) | 79.78 ± 5.59 | 64.86 ± 9.71 | ≤0.001 | | Females, n (%) | 8 (88.9) | 18 (21.7) | ≤0.001 | | Body mass index (kg/m2) | 23.04 ± 1.798 | 23.52 ± 1.97 | 0.49 | | History of AF, n (%) | 2 (22.2) | 18 (21.7) | 0.97 | | Hypertension, n (%) | 8 (88.9) | 43 (51.8) | 0.034 | | Diabetes, n (%) | 1 (11.1) | 18 (21.7%) | 0.46 | | Coronary artery disease, n (%) | 3 (33.3) | 12 (14,5) | 0.145 | | Pulmonary hypertension, n (%) | 7 (77.8%) | 20 (24.1) | 0.001 | | Echocardiography | | Mean LA size (mm) | 43.0 ± 4.33 | 40.38 ± 5.74 | 0.19 | | Mean IVS size (mm) | 11.67 ± 2.06 | 11.12 ± 2.05 | 0.45 | | Mean RV size (mm) | 22.33 ± 2.45 | 23.16 ± 3.18 | 0.454 | | Mean LV size (mm) | 41.0 ± 5.123 | 46.24 ± 7.13 | 0.035 | | Mean LVEF (%) | 60.78 ± 9.72 | 59.65 ± 9.85 | 0.745 | | Sinus of Valsalva diameter (mm) | 29.33 ± 2.87 | 30.77 ± 3.64 | 0.256 | | Aortic annular diameter (mm) | 19.33 ± 2.062 | 20.24 ± 2.22 | 0.244 | | Ascending aorta diameter (mm) | 32.22 ± 4.494 | 32.60 ± 3.71 | 0.775 | | Pulmonary artery diameter (mm) | 24.00 ± 3.00 | 23.67 ± 6.78 | 0.883 | | Blood tests | | Albumin (g/L) | 38.00 ± 3.91 | 39.20 ± 3.77 | 0.36 | | TC (mmol/L) | 3.90 ± 0.51 | 4.51 ± 1.07 | 0.008 | | LDL-c (mmol/L) | 2.26 ± 0.48 | 2.78 ± 0.92 | 0.099 | | HDL-c (mmol/L) | 1.14 ± 0.30 | 1.26 ± 0.33 | 0.288 | | Triglyceride (mmol/L) | 1.32 ± 0.35 | 1.18 ± 0.64 | 0.509 | | Fasting blood glucose (mmol/L) | 6.25 ± 1.50 | 6.20 ± 2.17 | 0.948 | | BNP (pg/mL) | 343.43 ± 273.36 | 245.00 ± 473.66 | 0.543 | | D-dimer (mg/L) | 1.22 ± 1.77 | 0.75 ± 0.76 | 0.447 | | Serum creatine (μmol/L) | 74.89 ± 16.91 | 88.08 ± 102.04 | 0.701 | | Blood urea nitrogen (mmol/L) | 7.45 ± 2.03 | 7.02 ± 5.05 | 0.803 | | Uric acid (mmol/L) | 388.22 ± 102.46 | 380.13 ± 114.46 | 0.839 | | Homocysteine (μmol/L) | 17.92 ± 9.06 | 14.25 ± 5.15 | 0.065 | | ALT (μ/L) | 19.78 ± 6.34 | 34.06 ± 71.65 | 0.553 | | AST (μ/L) | 22.11 ± 3.26 | 45.65 ± 183.33 | 0.705 | | WBC (∗109/L) | 6.99 ± 2.13 | 6.62 ± 1.63 | 0.527 | | Hemoglobin (g/L) | 137.78 ± 11.14 | 148.58 ± 17.44 | 0.073 | | Platelet (∗109/L) | 228.44 ± 35.51 | 217.35 ± 52.55 | 0.539 | | Medication use, n (%) | | ACEI or ARB, | 4 (44.4) | 27 (32.5) | 0.473 | | B-blocker | 6 (66.7) | 37 (44.6) | 0.207 | | Calcium-channel blocker | 6 (66.7) | 34 (41.0) | 0.140 | | Amiodarone | 4 (44.4) | 25 (30.1) | 0.380 |
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Values are mean ± SD, n (%), or mean (range). AF: atrial fibrillation; LA: left atrium; RV: right ventricular; LV: left ventricular; IVS: interventricular septum; LVEF: left ventricular ejection fraction; TC: total cholesterol; LDL-c: low-density lipoprotein cholesterol; HDL-c: high-density lipoprotein cholesterol; BNP: B-type natriuretic peptide; ALT: alanine transaminase; AST: aspartate transaminase; WBC: white blood cell count; ACEI: angiotensin-converting enzyme inhibitor; ARB: angiotensin receptor blockers.
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