Peripheral Artery Tonometry Reveals Impaired Endothelial Function before Percutaneous Coronary Intervention in Patients with Periprocedural Myocardial Injury
Table 1
Demographics and clinical characteristics.
Total (268)
RHI > 1.81 (131)
RHI ≤ 1.81 (137)
Age
62.9 ± 9.0
63.2 ± 8.8
62.6 ± 9.3
0.654
Male
185 (69.0)
87 (66.4)
98 (71.5)
0.365
Hypertension
170 (63.4)
80 (61.1)
90 (65.7)
0.432
Diabetes
60 (22.3)
28 (21.4)
32 (23.4)
0.697
Smoking history
95 (35.4)
42 (32.1)
53 (38.7)
0.257
BMI
24.7 ± 3.0
24.5 ± 3.2
24.9 ± 2.8
0.228
CAD
189 (70.5)
87 (66.4)
102 (74.5)
0.149
Syntax score
14.9 ± 8.0
12.0 ± 6.6
17.3 ± 8.3
<0.001
Coronary slow flow
11 (4.1)
4 (3.1)
7 (5.1)
0.396
Laboratory and auxiliary examinations
Systolic blood pressure (mmHg)
132.4 ± 12.3
131.6 ± 12.2
133.2 ± 12.4
0.592
Diastolic blood pressure (mmHg)
80.0 ± 8.2
79.0 ± 8.4
81.0 ± 8.0
0.100
NT-proBNP (pg/ml)
214.2 ± 536.7
215.1 ± 523.9
213.0 ± 550.6
0.461
Creatinine (mg/dl)
78.2 ± 16.9
76.8 ± 17.3
79.5 ± 16.6
0.187
CK (U/L)
94.4 ± 47.6
94.0 ± 50.8
94.8 ± 44.4
0.317
CK-MB (U/L)
12.9 ± 8.2
13.0 ± 10.2
12.7 ± 5.2
0.941
hs-CRP (mg/L)
3.94 ± 7.27
3.55 ± 7.17
4.35 ± 7.40
0.096
Hemoglobin (g/L)
134.4 ± 14.5
132.9 ± 13.9
135.9 ± 14.8
0.091
Platelet (×10^9/L)
207.5 ± 64.2
205.9 ± 62.1
209.0 ± 66.4
0.827
Total cholesterol (mmol/L)
3.82 ± 0.97
3.73 ± 0.86
3.91 ± 1.07
0.252
Low-density lipoprotein (mmol/L)
1.97 ± 0.81
1.94 ± 0.74
1.99 ± 0.87
0.892
Triglyceride (mmol/L)
1.77 ± 1.40
1.59 ± 0.96
1.94 ± 1.71
0.038
High-density lipoprotein (mmol/L)
1.14 ± 0.46
1.15 ± 0.57
1.13 ± 0.33
0.938
Lp (a) (mmol/L)
349.6 ± 485.8
351.8 ± 468.7
347.5 ± 503.5
0.370
HbA1c (%)
6.2 ± 1.4
6.1 ± 1.2
6.3 ± 1.5
0.111
Echocardiography
LA (mm)
38.9 ± 4.3
38.1 ± 4.4
39.5 ± 0.4
0.010
LVEDD (mm)
47.1 ± 4.5
46.5 ± 4.2
47.6 ± 4.8
0.050
LVESD (mm)
30.3 ± 4.3
30.0 ± 3.7
30.8 ± 4.8
0.090
SPAP (mmHg)
32.4 ± 6.3
32.7 ± 7.0
32.1 ± 5.7
0.784
EF (%)
64.4 ± 7.0
64.3 ± 7.3
64.5 ± 6.6
0.906
Medication
Statin
237 (88.4)
113 (86.3)
124 (90.5)
0.277
Β-blockade
175 (65.2)
86 (65.6)
89 (65.0)
0.906
Nitrates
132 (49.3)
59 (45.0)
73 (53.3)
0.177
Calcium channel blockade
68 (25.4)
35 (26.7)
33 (24.1)
0.621
Data are shown as mean ± SD or n (%). Slow flow was defined as a reduced thrombolysis in a myocardial infarction (TIMI) flow grade of 2 or lower in coronary angiography. BMI, body mass index; CAD, coronary artery disease; hs-CRP, hypersensitive C-reactive protein; EF, ejection fraction; LA, left atrium; LVEDD, left ventricular end-diastolic diameter; LVESD, left ventricular end-systolic diameter; Lp (a), lipoprotein (a); PMI, periprocedural myocardial injury; SPAP, systolic pulmonary arterial pressure.
