Peripheral Artery Tonometry Reveals Impaired Endothelial Function before Percutaneous Coronary Intervention in Patients with Periprocedural Myocardial Injury
Table 2
Baseline and procedural characteristics of PMI.
Total (119)
Non-PMI (68)
PMI (51)
Age
63.7 ± 9.5
64.0 ± 9.8
63.2 ± 9.3
0.476
Male
91 (76.4)
50 (73.5)
41 (80.4)
0.382
Hypertension
81 (68.1)
44 (64.7)
37 (72.5)
0.364
Diabetes
25 (21.0)
16 (23.5)
9 (17.5)
0.687
Smoking history
49 (41.1)
25 (36.8)
24 (47.1)
0.259
BMI
24.8 ± 3.2
24.7 ± 3.2
24.9 ± 3.3
0.573
Syntax score
15.2 ± 7.5
13.4 ± 6.3
17.4 ± 8.4
0.008
RHI
1.86 ± 0.46
1.95 ± 0.50
1.75 ± 0.37
0.039
Laboratory and auxiliary examinations
NT-proBNP (pg/ml)
225.1 ± 582.9
229.7 ± 735.7
219.2 ± 298.2
0.006
Creatinine (mg/dl)
78.3 ± 15.8
76.6 ± 15.0
80.6 ± 16.6
0.088
CK (U/L)
94.6 ± 45.6
96.0 ± 50.8
92.9 ± 38.3
0.658
CK-MB (U/L)
12.8 ± 3.8
12.8 ± 4.3
12.8 ± 3.1
0.596
hs-CRP (mg/L)
5.07 ± 9.41
3.95 ± 6.08
6.46 ± 12.3
0.691
Hemoglobin (g/L)
136.2 ± 14.1
135.4 ± 13.8
137.3 ± 14.7
0.512
Platelet (×10^9/L)
208.3 ± 68.2
205.4 ± 76.4
212.3 ± 56.0
0.262
Total cholesterol (mmol/L)
3.86 ± 1.02
3.70 ± 0.99
4.08 ± 1.03
0.032
Low-density lipoprotein (mmol/L)
2.04 ± 0.83
1.88 ± 0.77
2.24 ± 0.86
0.024
Triglyceride (mmol/L)
1.83 ± 1.70
1.97 ± 2.10
1.66 ± 0.92
0.912
High-density lipoprotein (mmol/L)
1.08 ± 0.30
1.06 ± 0.34
1.12 ± 0.24
0.025
Lp (a) (mmol/L)
339.2 ± 438.2
300.0 ± 298.6
391.8 ± 485.2
0.393
HbA1c (%)
6.1 ± 1.2
6.1 ± 1.4
6.1 ± 0.9
0.400
Echocardiography
LA (mm)
39.2 ± 4.2
39.2 ± 4.5
39.4 ± 3.8
0.900
LVEDD (mm)
46.7 ± 4.0
46.5 ± 4.5
47.2 ± 3.2
0.350
LVESD (mm)
30.2 ± 3.4
30.1 ± 3.6
30.4 ± 3.1
0.644
SPAP (mmHg)
32.9 ± 7.4
33.1 ± 8.2
32.6 ± 6.3
0.973
EF (%)
64.7 ± 6.1
65.0 ± 6.2
64.5 ± 6.2
0.529
Medication
Aspirin
115 (96.6)
64 (94.1)
51 (100)
0.134
Statin
118 (99.2)
67 (98.5)
51 (100)
1.000
Β-blockade
87 (73.1)
54 (79.4)
34 (66.7)
0.117
Nitrates
74 (62.2)
39 (57.4)
35 (68.6)
0.060
Calcium channel blockade
29 (24.3)
16 (23.5)
13 (25.5)
0.805
PCI
Stent length (mm)
44.4 ± 26.3
38.0 ± 21.5
52.8 ± 29.8
0.002
Use of GBI
20 (16.8)
11 (16.2)
9 (17.6)
0.832
Average stent diameter (mm)
3.06 ± 0.44
3.11 ± 0.45
2.99 ± 0.41
0.149
Target vessel number
1
96 (80.7)
58 (85.3)
38 (74.5)
0.140
2
20 (16.8)
9 (13.2)
11 (21.6)
0.229
3
3 (2.5)
1 (1.5)
2 (1.7)
0.576
Data are shown as mean ± SD or n (%). Slow flow was defined as a reduced thrombolysis in a myocardial infarction (TIMI) flow grade of 2 or lower in coronary angiography. BMI, body mass index; hs-CRP, hypersensitive C-reactive protein; GPI, glycoprotein IIb/IIIa receptor inhibitor; EF, ejection fraction; LA, left atrium; LVEDD, left ventricular end-diastolic diameter; LVESD, left ventricular end-systolic diameter; Lp (a), lipoprotein (a); PCI, percutaneous coronary intervention; SPAP, systolic pulmonary arterial pressure.
