Malapposed Struts with Cre8, Biomatrix, and Xience Stents Assessed with OCT Immediately after Implantation and at 6-Month Follow-Up: Can the Different Biomechanical Characteristics of the Three Stents Impact on Struts Malapposition?
Table 3
OCT analysis at the index PCI and comparison with OCT analysis at 6-month follow-up.
Cre8 (n = 14)
Biomatrix (n = 11)
Xience (n = 12)
value
Stent total length (mm), mean ± SD
20 ± 7.17
28 ± 8.92
30.3 ± 11.83
0.022 (A)
Overlapping stents, n (%)
3 (21)
3 (27)
4 (33)
N.S.
Cross sections analyzed (n)
Index PCI
221
186
207
N/A
Follow-up
217
179
203
N/A
Homogeneous distribution struts, n (%)
98.7 ± 3.3
97.5 ± 4.3
99.5 ± 1.6
0.348 (A)
Vessel wall injury, median (IQR)
0.0 (0.0–0.0)
0.0 (0.0–0.0)
0.0 (0.0–5.4)
0.010 (K-W)
Vessel lumen without thrombus, mean ± SD
97.9 ± 4.1
96.8 ± 4.3
96.2 ± 5.5
0.667 (A)
Protruding plaque, median (IQR)
9.1 (0.0–22.2)
0.0 (0.0–0.0)
10.5 (2.8–16.2)
0.097 (K-W)
Lipid plaque, median (IQR)
7.1 (0.0–15.8)
0.0 (0.0–6.7)
5.9 (0.0–13.6)
0.500 (K-W)
Calcified plaque, median (IQR)
0.0 (0.0–15.4)
0.0 (0.0–6.7)
0.0 (0.0–14.2)
0.579 (K-W)
Intimal dissection, median (IQR)
0.0 (0.0–0.0)
0.0 (0.0–0.0)
0.0 (0.0–0.0)
0.347 (K-W)
Struts analyzed (n)
Index PCI
2079
1615
1820
N/A
Follow-up
2041
1554
1782
N/A
Lumen area (mm2), mean ± SD
Index PCI
8.70 ± 2.26
8.66 ± 2.54
7.15 ± 1.40
0.138
Follow-up
8.05 ± 2.38
8.23 ± 2.87
7.77 ± 1.25
0.895
Follow-up versus Index, p (paired t-test)
0.800
0.744
0.094
Cross section with ISA
Index PCI, n (%)
7/220 (3.2)
3/186 (1.6)
7/207 (3.4)
0.509 χ2
Follow-up, n (%)
24/217 (11.05)
8/179 (4.5)
2/203 (0.9)
<0.001 χ2
value = 0.017
value=<0.001
Cre8 versus biomatrix
Xience versus Cre8
value = 0.033
Xience versus biomatrix
Malapposed struts
Index PCI
mean ± SD
0.57 ± 1.51
0.55 ± 1.81
0.58 ± 1.51
0.998 (A)
Median (IQR)
0.00 (0.00–0.00)
0.00 (0.00–0.00)
0.00 (0.00–0.00)
0.917 (K-W)
Follow-up
mean ± SD
3.29 ± 5.33
1.73 ± 2.28
0.25 ± 0.87
0.109 (A)
Median (IQR)
1.00 (0.00–4.00)
1.00 (0.00–3.00)
0.00 (0.00–0.00)
0.032 (K-W)
Follow-up versus Index
p (paired t-test)
0.023
0.024
0.166
p (Wilcoxon)
0.012
0.026
0.157
A : ANOVA; χ2: chi-square; N/A : not available; K-W: Kruskal–Wallis test. : Mann–Whitney U-test; .
