Research Article

Association of Early and Late Contrast-Associated Acute Kidney Injury and Long-Term Mortality in Patients Undergoing Coronary Angiography

Table 1

Baseline characteristics.

CharacteristicOverall (n = 3,206)Normal (n = 2,530)Late CA-AK (n = 322)Early CA-AKI (n = 354) value

Age, years63.75 (11.02)63.61 (10.97)63.52 (10.54)64.89 (11.73)0.1148
Age > 75, years (%)584 (18.22)441 (17.43)57 (17.70)86 (24.29)0.0071
Men, n (%)2271 (70.84)1828 (72.25)191 (59.32)252 (71.19)<0.001
Diabetes mellitus, n (%)886 (27.64)717 (28.34)76 (23.60)93 (26.27)0.1673
AMI, n (%)668 (20.85)542 (21.44)45 (13.98)81 (22.88)0.023
Hypertension, n (%)1744 (54.40)1408 (55.65)132 (40.99)204 (57.63)<0.001
CKD, n (%)498 (15.53)342 (16.85)67 (8.15)89 (25.14)<0.001
CHF, n (%)849 (26.69)616 (24.49)111 (34.91)122 (35.06)<0.0001
CAD, n (%)2371 (73.98)1968 (77.82)163 (50.62)240 (67.80)<0.001
PCI, n (%)1599 (49.88)1365 (53.95)97 (30.12)137 (38.70)<0.001
Vascular disease, n (%)713 (22.25)595 (23.54)54 (16.77)64 (18.08)<0.001
Anemia, n (%)161 (5.06)115 (4.61)19 (5.94)31 (8.81)<0.001
CMV, ml163.94 (112.43)169.90 (112.32)119.10 (98.03)162.15 (116.40)<0.001
LDLC, mmol/L2.79 (0.96)2.81 (0.99)2.72 (0.85)2.78 (0.88)0.3550
HDLC, mmol/L0.99 (0.28)0.99 (0.28)1.03 (0.31)0.99 (0.28)0.0485
Cys-C, mg/L1.43 (0.81)1.36 (0.74)1.69 (0.91)1.95 (1.18)<0.0001
eGFR, ml/min/1.73 m268.74 (28.58)69.59 (27.83)66.82 (29.83)64.38 (32.07)0.0025
Creatine kinase, U/L261.66 (598.67)92.00 (59.05, 164.50)82.00 (54.00, 191.25)96.00 (59.00, 176.30)0.2441
NT-proBNP, pg/mL3724.79 (7141.08)877.50 (187.15, 3045.00)1359.00 (527.80, 4260.00)1684.00 (536.80, 5173.00)<0.001
877.50 (187.15, 3045.00)1359.00 (527.80, 4260.00)1684.00 (536.80, 5173.00)
NYHA class > 11791 (92.22)1373 (91.29)216 (94.74)202 (96.19)0.0147
Beta-blocker use1839 (60.67)1515 (62.17)149 (51.20)175 (57.76)<0.001
Statin use2094 (69.09)1817 (74.56)108 (37.11)169 (55.78)<0.001
Diuretic use1300 (42.89)893 (36.64)219 (75.26)188 (62.05)<0.001
ACEI/ARB use1608 (53.05)1400 (57.45)93 (31.96)115 (37.95)<0.001

Abbreviations: AMI, acute myocardial infarction; CKD, chronic kidney disease; CHF, chronic heart failure; CAD, coronary artery disease; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; LVEF, left ventricular ejection fraction; eGFR, estimated glomerular filtration rate; BUN, blood urea nitrogen; PCI, percutaneous coronary intervention; CMV, contrast media volume; ACEI/ARB, angiotensin-converting enzyme inhibitor/angiotensin receptor blocker.