Impact of Coronary Artery Disease and Percutaneous Coronary Intervention on Transcatheter Aortic Valve Implantation
Table 1
Baseline characteristics.
Whole population
CAD group
No CAD group
value CAD versus no CAD
N = 1030
N = 372
N = 658
Age
84.3 ± 7
84.2 ± 7
84.6 ± 7
0.35
Male
466 (45.2)
196 (52.7)
270 (41)
<0.001
Hypertension
708 (68.7)
253 (68)
455 (69.1)
0.7
Diabetes mellitus
264 (74.4)
108 (29)
156 (23.7)
0.05
Dyslipidemia
410 (39.8)
175 (47)
235 (35.7)
<0.001
Smoking
26 (2.5)
6 (1.6)
20 (3)
0.16
BMI
26.2 ± 5
26.2 ± 4.9
30.7 ± 4.7
0.27
Chronic respiratory disease
193 (18.7)
61 (16.4)
132 (20.1)
0.14
Atrial fibrillation
394 (38.3)
130 (34.9)
264 (40.1)
0.1
Prior stroke
110 (10.7)
41 (11)
69 (10.5)
0.78
Prior PAD
69 (6.7)
31 (8.3)
38 (5.8)
0.11
EuroScore1
14.2 ± 9.9
14.3 ± 10
14 ± 10
0.84
STS-PROM
6.35 ± 4.7
6.3 ± 4.7
5.7 ± 5.5
0.68
Baseline LVEF
53.7 ± 11.8
53.2 ± 12.3
53.7 ± 11.5
0.07
Antithrombotic treatment
None
247 (24)
35 (9.4)
212 (32.2)
<0.001
Single-antiplatelet therapy
245 (23.8)
65 (17.5)
180 (27.4)
Dual-antiplatelet therapy
171 (16.6)
156 (41.9)
15 (2.3)
Anticoagulation therapy
278 (27)
49 (13.2)
229 (34.8)
Antiplatelet + anticoagulation
89 (8.6)
67 (18)
22 (3.3)
TAVI approach
Transfemoral
967 (93.9)
349 (93.8)
618 (93.9)
0.22
Transaortic
54 (5.2)
18 (4.8)
36 (5.5)
Transapical
2 (0.2)
0 (0)
2 (0.3)
Transsubclavian
5 (0.5)
4 (1.1)
1 (0.2)
Transcarotid
2 (0.2)
1 (0.3)
1 (0.2)
Valve in valve
35 (3.4)
14 (3.8)
21 (3.2)
0.62
Prosthesis type
Ballon expandable
560 (54.4)
217 (58.3)
343 (52.1)
0.05
Self-expanding
470 (45.6)
155 (41.7)
315 (47.9)
Post-TAVI LVEF
54.9 ± 10.7
54.7 ± 10.7
55.6 ± 10.9
0.85
CAD = coronary artery disease. BMI = body mass index. PAD = peripheral artery disease. LVEF = left ventricle ejection fraction. EuroScore = European System for Cardiac Operative Risk Evaluation. STS-PROM = Society of Thoracic Surgeons Predicted Risk of Mortality. TAVI = transcatheter aortic valve implantation. CCU = cardiac care unit. TAVI: transcatheter aortic valve implantation. CAD: coronary artery disease. PCI: percutaneous coronary intervention.
