Research Article

Diagnostic Performance of Frequency-Domain Optical Coherence Tomography to Predict Functionally Significant Left Main Coronary Artery Stenosis

Table 1

Baseline clinical and angiographic characteristics of the study population.

Patients (n = 101)Patients
FFR ≤0.80
(n = 
42)
Patients
FFR >0.80
(n = 
59)
value

Baseline characteristics
Age (years)63.18 ± 9.862.38 ± 9.863.75 ± 9.80.493
Male, n (%)60 (59.4)24 (57.1)36 (61.0)0.696
Hypertension, n (%)56 (55.4)19 (45.2)37 (62.7)0.082
Diabetes, n (%)34 (33.7)18 (42.9)16 (27.1)0.099
Dyslipidemia, n (%)76 (75.2)30 (71.4)46 (78.0)0.453
Current smoker, n (%)59 (58.4)22 (52.4)37 (62.7)0.299
Family history, n (%)45 (44.6)14 (33.3)31 (52.5)0.056
LV ejection fraction (%)50.45 ± 9.050.71 ± 7.950.25 ± 9.90.803
Acute coronary syndrome, n (%)32 (31.7)14 (33.3)18 (30.5)0.961
Prior myocardial infarction, n (%)9 (9.0)5 (12.0)4 (6.8)0.187
Prior coronary intervention, n (%)49 (48.5)24 (57.1)125 (42.4)0.143
Proximal lesion LM, n (%)30 (29.7)14 (33.3)16 (27.1)0.501

Angiographic characteristics
Total LM length, mm14.23 ± 5.215.13 ± 5.413.59 ± 4.90.142
LM lesion length, mm3.09 ± 1.43.57 ± 1.42.73 ± 1.30.003
LM reference lumen diameter, mm3.89 ± 0.73.92 ± 0.73.87 ± 0.60.677
LM minimum lumen diameter, mm2.09 ± 0.51.94 ± 0.52.19 ± 0.40.010
LM % diameter stenosis45.74 ± 11.350.22 ± 10.742.56 ± 10.60.001
Mean FFR value0.83 ± 0.070.75 ± 0.020.89 ± 0.03<0.001

Values are presented as n (%) or mean ± standard deviation (SD). FFR = fractional flow reserve; LM = left main; LV = left ventricle.