Research Article

Contemporary Strategies and Outcomes of Dedicated Chronic Total Occlusion Percutaneous Coronary Intervention Programs: A Prospective Multicentre Registry

Table 2

In-hospital complications.

All (n = 920)Years 1–4 (n = 301)Years 5–9 (n = 619) value

Any complication86 (9.3)23 (7.6)63 (10.2)0.230
Major complication43 (4.7)9 (3.0)34 (5.5)0.098
Major adverse cardiovascular events23 (2.5)4 (1.3)19 (3.1)0.175
 In-hospital death3 (0.3)1 (0.3)2 (0.3)1.0
 Stroke2 (0.2)1 (0.3)1 (0.2)0.548
 Periprocedural MI18 (2.0)2 (0.7)16 (2.6)0.072

Coronary complications37 (4.0)13 (4.3)24 (3.9)0.724
 CTO vessel27 (2.9)10 (3.3)17 (2.7)0.678
 Donor vessel10 (1.1)3 (1.0)7 (1.1)1.0
 Coronary perforation28 (3.0)10 (3.3)18 (2.9)0.838
  Ellis type 2 or more18 (2.0)8 (2.7)10 (1.6)0.314
  Requiring intervention12 (1.3)3 (1.0)9 (1.5)0.760

Vascular complications30 (3.3)6 (2.0)24 (3.9)0.166
 Retroperitoneal hematoma3 (0.3)1 (0.3)2 (0.3)1.0
 Hematoma > 5 cm12 (1.3)5 (1.7)7 (1.1)0.542
 Pseudoaneurysm12 (1.3)0 (0)12 (1.9)0.011
 Acute limb ischemia3 (0.3)0 (0.5)3 (0.5)0.555

Major vascular complication9 (1.0)3 (1.0)6 (1.0)1.0

Others
 Pericardial effusion16 (1.7)6 (2.0)10 (1.6)0.789
 Major bleeding9 (1.0)3 (1.0)6 (1.0)1.0
 Contrast-induced nephropathy16 (1.7)4 (1.3)12 (1.9)0.601

Myocardial injury
 hsTroponin T, baseline (ng/L)15 (9–30)18 (10–40)14 (9–25)0.003
 hsTroponin T, day 1 (ng/L)43 (22–110)33 (18–90)50 (24–127)<0.001
 Coronary procedure-related myocardial injury462 (71.0)154 (61.1)308 (77.2)<0.001

CTO, chronic total occlusion; hsTroponin T, high-sensitivity troponin T; MI, myocardial infarction. Troponin values are median with interquartile range. Dichotomous variables are reported as number (percentages). Significant p values below 0.05 are shown in bold.