Effect of Renal and Left Ventricular Function on Serial Pulmonary Arterial Pressure Changes after Device Closure of Atrial Septal Defect

Table 1

Baseline clinical characteristics and echocardiographic measurements in patients with ASD.

Variable (n = 78)	Parameter
Age, years	49.8 ± 15.0
Female, n (%)	51 (65)
Body mass index, kg/m^2	22.4 ± 3.0
Systolic blood pressure, mmHg	116.5 ± 15.7
Blood urea nitrogen, mg/dL	15.1 ± 4.4
Creatinine, mg/dL	0.75 ± 0.16
eGFR, mL/min/1.73 m²	99.8 ± 18.8
Atrial fibrillation, n (%)	6 (8)
LV mass index, g/m^2	63.3 ± 16.3
LA volume index, mL/m^2	30.5 ± 12.5
LV ejection fraction, %	66.1 ± 6.4
Stroke volume, mL	52.1 ± 11.2
TRV, m/sec	2.73 ± 0.48
PASP, mmHg	37.0 ± 12.3
PVR, Wood unit	1.47 ± 0.31
e’, cm/s	9.3 ± 3.2
E/e’	9.0 ± 3.5
More than single defects, n (%)	4 (5)
ASD maximal defect diameter, mm	20.2 ± 6.0
ASD defect area, cm^2	2.57 ± 1.52
ASD device diameter, mm	23.8 ± 6.4
Qp/Qs ratio	2.52 ± 0.85
Procedure guidance by TEE/ICE	64/14
Amplatzer, Abbott/Cocoon, Vascular Innovations/Figulla Flex II, Occlutech/Helex, Gore	41/33/3/1

ASD, atrial septal defect; e’, early diastolic septal mitral annular velocity; E/e’, ratio of early mitral inflow velocity to e’; ICE, intracardiac echocardiography; LA, left atrial; LV, left ventricular; PASP, pulmonary arterial systolic pressure; PVR, pulmonary vascular resistance; TEE, transesophageal echocardiography; TRV, tricuspid regurgitant velocity.