Effect of Renal and Left Ventricular Function on Serial Pulmonary Arterial Pressure Changes after Device Closure of Atrial Septal Defect

Table 2

Comparisons between groups according to new-onset atrial fibrillation after device closure and diuretics use.

Variable	New-onset AF after closure (n = 4)	No AF (n = 68)	value	Diuretics use (n = 5)	No diuretics use (n = 73)	value
Age, years	60.0 ± 10.5	47.9 ± 14.9	0.113	58.8 ± 13.7	49.2 ± 15.0	0.124
Female, n (%)	2 (50)	45 (66)	0.509	3 (60)	48 (66)	0.794
Past history of AF, n (%)				4 (80)	2 (3)	<0.001
eGFR, mL/min/1.73 m²	90.0 ± 10.6	102.8 ± 17.4	0.085	80.8 ± 14.1	101.2 ± 18.4	0.018
Maximal defect diameter, mm	23.0 ± 5.9	20.4 ± 6.0	0.308	20.0 ± 4.7	20.2 ± 6.2	0.886
Defect area, mm^2	298.1 ± 110.8	262.1 ± 155.8	0.433	264.9 ± 151.4	256.5 ± 153.5	0.975
Device diameter, mm	26.0 ± 3.7	24.0 ± 6.5	0.491	22.8 ± 4.6	23.9 ± 6.5	0.779
LV mass index, g/m^2	65.9 ± 17.5	62.8 ± 16.5	0.525	55.6 ± 14.4	63.9 ± 16.4	0.295
LA volume index, mL/m^2	35.8 ± 6.5	28.1 ± 9.3	0.065	39.4 ± 20.4	29.9 ± 11.7	0.205
LV ejection fraction, %	62.3 ± 4.3	66.3 ± 6.6	0.198	65.4 ± 5.3	66.2 ± 6.5	0.772
Stroke volume, mL	51.6 ± 9.4	53.1 ± 10.7	0.832	40.7 ± 14.9	53.0 ± 10.5	0.038
TRV, m/sec	2.63 ± 0.36	2.72 ± 0.49	0.765	2.89 ± 0.56	2.72 ± 0.48	0.004
PASP, mmHg	36.8 ± 4.8	36.3 ± 12.6	0.549	45.5 ± 12.7	36.4 ± 12.2	0.306
PVR, Wood unit	1.24 ± 0.43	1.45 ± 0.27	0.336	1.91 ± 0.41	1.44 ± 0.28	0.088
e’, cm/s	8.8 ± 3.5	9.3 ± 3.3	0.787	8.9 ± 1.7	9.3 ± 3.3	0.974
E/e’	10.7 ± 6.9	8.5 ± 3.0	0.681	11.5 ± 3.1	8.8 ± 3.4	0.038

AF, atrial fibrillation; see abbreviations in Table 1. Patients with pre-existing AF were excluded; ^†Mann–Whitney test for nonparametric comparisons.