Research Article

High-Dose Atorvastatin Raises Threshold of Contrast-Induced Nephropathy in Diabetic Patients Undergoing Elective Coronary Intervention: A Randomized Controlled Study

Table 1

The baseline demographic, clinical, echocardiographic, and laboratory data of the studied population.

Parameter

Age in years (mean ± SD)58.8 ± 7.8
Sex, males (%)94 (47)
Smokers (%)39 (19.5)
HTN (%)77 (38.5)
Previous PCI (%)8 (4)
Duration of DM in years (mean ± SD)7 ± 3.9
Insulin therapy (%)95 (47.5)
Heart failure (%)44 (22)
Body mass index (mean ± SD)27.2 ± 3.3
Heart rate in beats/min. (mean ± SD)84.5 ± 14.5
Systolic blood pressure in mmHg (mean ± SD)132.9 ± 18.8
Diastolic blood pressure in mmHg (mean ± SD)83.9 ± 10.4
Segmental wall motion abnormalities (%)68 (34)
EF (%) (mean ± SD)59.3 ± 9.8
Volume of contrast in ml (mean ± SD)121.4 ± 48.3
Time of X-ray exposure in min. (mean ± SD)12 ± 5.5

Coronary procedure
PCI with one stent133 (66.5)
PCI with two stents53 (26.5)
PCI with more than two stents14 (7)

TIMI flow
TIMI I2 (1)
TIMI II9 (4.5)
TIMI III189 (94.5)
Baseline serum creatinine in umol/L (mean ± SD)119.1 ± 16.8
Follow-up serum creatinine in umol/L (mean ± SD)136.1 ± 25.6
Hemoglobin in mg/dL (mean ± SD)12.3 ± 1.6
CIN (%)24 (12)