Impact of Arterial Remodeling of Intermediate Coronary Lesions on Long-Term Clinical Outcomes in Patients with Stable Coronary Artery Disease: An Intravascular Ultrasound Study

Table 2

IVUS measurements.

	Remodeling of intermediate lesions			value
	IR (n = 72)	NR (n = 77)	PR (n = 63)	NR vs. IR	NR vs. PR	IR vs. PR
Vessel
LAD, n (%)	51 (70.8)	55 (71.4)	43 (68.3)	0.94	0.68	0.75
LCX, n (%)	7 (9.7)	9 (11.7)	5 (7.9)	0.7	0.46	0.72
RCA, n (%)	14 (19.4)	13 (16.9)	15 (23.8)	0.69	0.31	0.54
Morphological analysis
Soft, n (%)	12 (16.7)	13 (16.9)	22 (34.9)	0.97	0.01	0.01
Fibrous, n (%)	30 (41.67)	24 (31.2)	13 (20.63)	0.18	0.16	0.01
Calcified, n (%)	2 (2.78)	5 (6.49)	4 (6.35)	0.28	0.97	0.32
Mixed, n (%)	28 (38.9)	35 (45.45)	24 (38.1)	0.42	0.38	0.92
Attenuated plaque, n (%)	7 (9.72)	11 (14.29)	20 (31.75)	0.39	0.01	<0.01
Plaque rupture, n (%)	1 (1.39)	0 (0)	1 (1.59)	0.3	0.27	0.92
Lesion length	16.73 ± 6.79	17.00 ± 6.33	19.23 ± 7.56	0.8	0.05	0.04
Remodeling index	0.94 ± 0.04	0.76 ± 0.09	1.15 ± 0.12	<0.01	<0.01	<0.01
Minimal lumen site
EEM CSA (mm^2)	15.27 ± 4.46	11.54 ± 2.92	17.35 ± 6.20	<0.01	<0.01	0.025
Lumen CSA (mm^2)	5.05 ± 1.39	4.16 ± 1.03	4.85 ± 1.76	<0.01	<0.01	0.48
Area stenosis (%)	54.61 ± 9.09	59.32 ± 10.15	51.67 ± 12.96	<0.01	<0.01	0.13
Plaque burden (%)	66.12 ± 6.82	63.45 ± 6.13	71.17 ± 6.45	0.01	<0.01	<0.01
Eccentricity	0.84 ± 0.13	0.79 ± 0.17	0.82 ± 0.16	0.04	0.18	0.53
Reference site
EEM CSA at proximal reference (mm^2)	17.84 ± 5.43	17.03 ± 5.04	16.81 ± 5.93	0.34	0.82	0.3
EEM CSA at distal reference (mm^2)	14.83 ± 4.97	13.36 ± 3.90	13.19 ± 5.17	0.046	0.84	0.07
Lumen CSA at proximal reference (mm^2)	12.22 ± 3.68	11.69 ± 3.91	11.32 ± 4.36	0.4	0.6	0.2
Lumen CSA at distal reference (mm^2)	10.39 ± 3.35	9.60 ± 2.87	9.59 ± 3.22	0.13	0.97	0.16

CSA, cross-sectional area; EEM, external elastic membrane; IR, intermediate remodeling; NR, negative remodeling; PR, positive remodeling.