Old Is (Not) Gold: Midazolam Monotherapy versus Midazolam Plus Fentanyl for Sedation during Cardiac Catheterization

Table 2

Comparison of independent groups on primary and secondary endpoints.

Outcome	M; N = 69	M + F; N = 60	Mean difference (95% CI)	value
Pain during procedure, n (%)	18 (26.09%)	17 (28.33%)	—	0.78
Pain severity (1–10)	1.1 (2.0)	1.1 (2.3)	−0.25 (−0.77–0.72)	0.95
Premidazolam (mg)	1.73 (1.02)	1.59 (0.96)	0.14 (−0.21–0.49)	0.43
Prefentanyl (mg)	0 (0)	50 (25)	—	0^†
Total midazolam (mg)	3.71 (2.02)	3.43 (1.93)	0.28 (−0.42–0.97)	0.43
Total fentanyl (mg)	0 (0)	75 (50)	—	0^†
Total procedure time (mins)	41.88 (34.40)	38.62 (26.19)	3.27 (−7.51–14.05)	0.55

Values are mean (standard deviation). Values are frequency (percentage). ^†. M, midazolam group; M + F, midazolam plus fentanyl group. ^† value could not be calculated as fentanyl was not provided in the midazolam only group.