COlchicine to Prevent PeriprocEdural Myocardial Injury in Percutaneous Coronary Intervention (COPE-PCI): Coronary Microvascular Physiology Pilot Substudy

Figure 1

Overview of study design and patient allocation. (i) Development of unstable troponin or active inflammation/infection, anti-inflammatory medications given, or inappropriate blood sampling occurred in 14 patients after randomization. (ii) Cardiac conference discussion = patient had severe CAD at coronary angiography. The procedure was therefore stopped, and the patient's case was discussed at a later date at a combined cardiology/cardiothoracic surgical meeting to determine an optimal revascularization strategy. Most patients were sent for coronary artery bypass grafting. (iii) Other PCI exclusion criteria = see “exclusion criteria” in the supplemental material. (iv) Complex PCI case = as deemed by the interventional cardiologist, not appropriate for coronary artery physiology measurements.