Research Article

COlchicine to Prevent PeriprocEdural Myocardial Injury in Percutaneous Coronary Intervention (COPE-PCI): Coronary Microvascular Physiology Pilot Substudy

Table 2

PCI characteristics, by study drug randomization.

PCI characteristicsColchicine (n = 24)Placebo (n = 26) value

Access
 Radial20 (83)21 (81)1||
 Femoral4 (17)5 (19)1||
PCI artery
 Left anterior descending13 (54)12 (46)0.57§
 Intermediate2 (8)0 (0)0.23||
 Left circumflex5 (21)6 (23)1||
 Right coronary artery4 (17)8 (31)0.33||
 PCI procedure duration (minutes)55 (47–69)62 (51–70)0.25
 Contrast volume (mL)150 (120–200)160 (120–193)0.86
 Total number of balloon inflations7.0 (5.0–11.0)6.0 (5.0–9.0)0.86
 Total time of balloon inflations (seconds)66 (48–80)69 (51–91)0.78
 Total stent length (mm)18 (15–24)23 (18–32)0.07
 Maximum stent diameter (mm)3.28 (2.95–3.99)3.33 (3.00–3.64)0.88
Stent type
 Drug-eluting stent23 (96)26 (100)0.48||
 Bare metal stent1 (4)0 (0)0.48||
 Pre-PCI balloon dilation23 (96)25 (96)1||
 Post-PCI balloon dilation22 (92)24 (92)1||
 Use of OCT or IVUS00
PCI complications
 Stent dissection1/23 (4)1 (4)1||
 No reflow00

Values are n/N (%), mean ± SD or median (LQ-UQ), stent dissection assessed by angiography, denotes comparison between colchicine vs placebo group, † denotes independent-samples t-test, ‡ denotes Mann–Whitney-U test, § denotes Chi-squared test, and || denotes Fisher’s exact test.