Long-Term Outcomes after Rotational Atherectomy for Calcified Chronic Total Occlusion versus Nonchronic Total Occlusion Coronary Lesions

Table 5

Univariate and multivariate regression analyses identifying predictors of the long-term target lesion failure (TLF).

	Univariate analysis; hazard ratio (95% CI)		value	Multivariate analysis; hazard ratio (95% CI)		value
Age	1.02	(0.99–1.04)	0.180
Male sex	1.23	(0.79–1.91)	0.367
DM	1.763	(1.19–2.59)	0.004	1.47	(0.99–2.18)	0.056
HTN	0.564	(0.33–0.98)	0.041	0.53	(0.31–0.93)	0.026
Smoking	1.275	(0.86–1.91)	0.235
Dyslipidemia	1.09	(0.72–1.65)	0.696
CKD	1.69	(1.07–2.69)	0.025	1.72	(1.08–2.74)	0.023
EF < 50%	1.78	(1.20–2.63)	0.004	1.59	(1.07–2.34)	0.023
CTO lesion	1.82	(1.02–3.26)	0.044	2.04	(1.13–3.69)	0.018
Multivessel disease	1.74	(0.88–3.45)	0.110
Periprocedural MI	2.72	(1.46–5.09)	0.002	2.46	(1.28–4.76)	0.007
Slow flow	1.82	(0.79–4.14)	0.156
Perforation	1.69	(0.62–4.58)	0.306
Bifurcation	1.12	(0.76–1.654)	0.562
Ostial lesion	1.41	(0.94–2.13)	0.098	1.25	(0.82–1.92)	0.297
Stent length	1.00	(0.99–1.01)	0.525
Bailout RA	1.08	(0.73–1.59)	0.712
Early generation DES	0.957	(0.62–1.48)	0.845

Data are presented as hazard ratio and 95% confidence interval. CAD, coronary artery disease; CKD, chronic kidney disease; CTO, chronic total occlusion; DES, drug-eluting stent; DM, diabetes mellitus; EF, ejection fraction; GFR, glomerular filtration rate; HTN, hypertension; MI, myocardial infarction; PCI, percutaneous coronary intervention; RA, rotational atherectomy.