Thrombotic vs. Bleeding Events of Interruption of Dual Antiplatelet Therapy within 12 Months among Patients with Stent-Driven High Ischemic Risk Definition following PCI
Table 3
Lesion and procedural characteristics.
Interruption of DAPT within 12 months after PCI
value
No (n = 2809)
Yes (n = 1122)
Lesion characteristics
Multivessel CAD
2525 (89.9)
998 (88.9)
0.382
Location of the lesion treated
LM
140 (5.0)
50 (4.5)
0.486
LAD
2386 (84.9)
964 (85.9)
0.436
LCx
835 (29.7)
348 (31.0)
0.426
RCA
959 (34.1)
371 (33.1)
0.520
Bypass graft
7 (0.2)
3 (0.3)
0.919
Target lesion morphology
Heavy calcified lesion
143 (5.1)
55 (4.9)
0.807
In-stent restenosis lesion
128 (4.6)
49 (4.4)
0.796
Bifurcation lesion
569 (20.3)
221 (19.7)
0.693
Bifurcation with two stents implanted
283 (10.1)
98 (8.7)
0.200
Thrombotic lesion
116 (4.1)
52 (4.6)
0.480
Chronic total occlusion
541 (19.3)
194 (17.3)
0.153
Type B2 or C lesion
2510 (89.4)
1020 (90.9)
0.146
SYNTAX score
14.67 ± 8.46
14.51 ± 8.26
0.629
Total lesion length, mm
57.22 ± 30.35
55.76 ± 27.88
0.163
Procedural characteristics
Number of vessels treated
1.49 ± 0.60
1.50 ± 0.59
0.566
Number of lesions treated
1.75 ± 0.81
1.75 ± 0.81
1.000
1
1241 (44.1)
501 (44.7)
0.787
2
1111 (39.6)
432 (38.5)
0.543
≥3
458 (16.3)
189 (16.8)
0.680
Number of stents implanted
2.66 ± 1.16
2.59 ± 1.13
0.105
1
429 (15.3)
189 (16.8)
0.221
2
863 (30.7)
343 (30.6)
0.926
≥3
1517 (54.0)
590 (52.6)
0.420
Total stent length, mm
61.00 ± 29.34
59.99 ± 27.90
0.327
Total stent length > 60 mm
1280 (45.9)
523 (46.6)
0.666
Mean stent diameter, mm
2.92 ± 0.52
2.91 ± 0.54
0.640
Vascular access site
0.459
Radial approach
2538 (90.4)
1005 (89.6)
Femoral approach
271 (9.6)
117 (10.4)
Use of intravascular ultrasound
214 (7.6)
91 (8.1)
0.602
Use of glycoprotein IIb/IIIa inhibitors
520 (18.5)
223 (19.9)
0.324
Drug-eluting stent type
0.949
First-generation DES
286 (10.2)
115 (10.2)
Second-generation DES
2523 (89.8)
1007 (89.8)
Values are mean ± SD for continuous variables and n (%) for categorical variables. CAD indicates coronary artery disease; DES, drug-eluting stent; LM, left main coronary artery; LAD, left anterior descending coronary artery; LCx, left circumflex coronary artery; RCA, right coronary artery; and SYNTAX, Synergy between PCI with Taxus and Cardiac Surgery.
