Research Article

Sex Difference in Coronary Artery Spasm Tested by Intracoronary Acetylcholine Provocation Test in Patients with Nonobstructive Coronary Artery Disease

Table 4

Various clinical outcomes of coronary artery spasm up to 5-year by Kaplan–Meier curve analysis.

Outcomes, incidence (%)Overall patientsMatched patients
Male (n = 1575)Female (n = 1535)Log rankMale (n = 713)Female (n = 713)Log rank

MACE13 (1.2)7 (0.6)0.2014 (0.8)3 (0.6)0.688
Total death5 (0.4)3 (0.3)0.5021 (0.1)2 (0.4)0.581
Cardiac death2 (0.1)1 (0.0)0.5780 (0.0)1 (0.1)0.322
Myocardial infarction; MI4 (0.2)2 (0.1)0.4321 (0.2)0 (0.0)0.316
CAS-induced MI4 (0.2)1 (0.0)0.1870 (0.0)0 (0.0)
De novo PCI5 (0.6)2 (0.1)0.2783 (0.7)0 (0.0)0.081
Recurrent angina104 (10.7)77 (7.8)0.05941 (9.4)29 (5.3)0.127

MACE, major adverse cardiac events; CAS, coronary artery spasm; PCI, percutaneous coronary intervention.