Selective Use of Pulmonary Vasodilators in Patients with Fontan Physiology

Table 4

Liver biopsy data.

	Patient 1	Patient 2	Patient 3
Pretherapy histological findings	Mild focal sinusoidal fibrosis, mild chronic inflammation, and mild sinusoidal dilation	Diffuse sinusoidal fibrosis, moderate portal fibrosis, mild chronic inflammation, and mild sinusoidal dilation	Moderately severe sinusoidal fibrosis, mild portal fibrosis, and mild sinusoidal dilation
Modified ISHAK (ICHF) score [16] pretherapy	1	3	2A
Posttherapy histological findings	Severe focal sinusoidal fibrosis, severe portal fibrosis, and mild sinusoidal dilation	Mild sinusoidal fibrosis mild portal fibrosis, moderate chronic inflammation	Mild sinusoidal fibrosis; moderate sinusoidal dilation
Modified ISHAK (ICHF) score [16] posttherapy	5	3	1