Clinical Features and Long-Term Outcomes in Very Young Patients with Myocardial Infarction with Non-Obstructive Coronary Arteries

Table 1

Clinical characteristics of patients ≤40 years old undergoing coronary angiography.

Variables	oCAD (n = 250)	MINOCA (n = 32)	Controls (n = 126)	value oCAD vs controls	value MINOCA vs controls	value oCAD vs MINOCA
Age (median and IQR)	37 (34–39)	35 (33–38)	34 (32–39)	0.019	0.862	0.194
Women	28 (11.2%)	7 (21.9%)	17 (13.5%)	0.518	0.238	0.085
Body max index >30	82 (32.8%)	10 (31.3%)	35 (27.8%)	0.321	0.698	0.860
Hypertension	54 (21.6%)	5 (15.6%)	25 (19.8%)	0.693	0.587	0.434
Diabetes	16 (6.4%)	1 (3.1%)	6 (4.8%)	0.523	0.688	0.464
Smoking	213 (85.2%)	24 (75.0%)	78 (61.9%)	<0.001	0.167	0.138
Dyslipidemia	124 (49.6%)	11 (34.4%)	28 (22.2%)	<0.001	0.154	0.105
Family history of CAD	72 (28.8%)	7 (21.9%)	15 (11.9%)	<0.001	0.146	0.411
Illicit drugs and alcohol	56 (22.4%)	9 (28.1%)	26 (20.6%)	0.696	0.362	0.469
Cannabis	30 (12.0%)	4 (12.5%)	8 (6.3%)	0.086	0.241	0.935
Opioids	4 (1.6%)	1 (3.1%)	3 (2.4%)	0.597	0.811	0.538
Alcohol	26 (10.4%)	5 (15.6%)	12 (9.5%)	0.790	0.320	0.374
Cocaine	28 (11.2%)	5 (15.6%)	10 (7.9%)	0.322	0.185	0.463
Peripheral artery disease	3 (1.2%)	0 (0.0%)	1 (0.8%)	0.717	0.613	0.533
Congestive heart failure	1 (0.4%)	0 (0.0%)	1 (0.8%)	0.620	0.613	0.720
Previous stroke	2 (0.8%)	0 (0.0%)	1 (0.8%)	0.995	0.613	0.612
Atrial fibrillation	2 (0.8%)	0 (0.0%)	1 (0.8%)	0.995	0.613	0.612
Renal failure	6 (2.4%)	1 (3.1%)	9 (7.1%)	0.027	0.405	0.804
Depression	16 (6.4%)	5 (15.6%)	11 (8.7%)	0.409	0.248	0.061

Data are given as number (percentage) or mean ± SD. oCAD, obstructive coronary artery disease. CAD, coronary artery disease.