LysoPC and PAF Trigger Arachidonic Acid Release by Divergent Signaling Mechanisms in Monocytes
Figure 3
LysoPC- and PAF-mediated [3H]AA release is inhibited by different alcohols. Prelabeled THP-1 cells were preincubated with different alcohols 30 min before challenge with lysoPC (40 μM, 10 min) or PAF (35 μM, 5 min). [3H]AA release in the medium was measured by liquid scintillation counting. Data are expressed as means ± SD of triplicate determinations within separate experiments. Asterisks indicate that values are statistically different from PAF- or lysoPC-treated cells (*).
