Hydroxyurea Therapy Mobilises Arachidonic Acid from Inner Cell Membrane Aminophospholipids in Patients with Homozygous Sickle Cell Disease

Table 2

Plasma lipid concentrations of steady state HU treated HbSS sickle cell patients and HbAA healthy controls.

Plasma lipids	HbAA (𝑛=20)	HbSS (𝑛=17)
LDL-cholesterol (mmol/L)	2.4 ± 0.5	1.7 ± 0.7**
HDL-cholesterol (mmol/L)	1.1 ± 0.3	0.8 ± 0.2***
Total cholesterol (mmol/L)	3.71 ± 0.56	2.7 ± 0.8***
Triacylglycerol (mmol/L)	1.01 ± 0.4	1.24 ± 0.03

HbSS patients versus HbAA controls: **𝑃<0.01, ***𝑃<0.001;